S.P.E.C.I.E.S. · DE
Area of research
Pulmonary and Respiratory Medicine
Research interest
Research interests include Pulmonary Hypertension Research and Treatments, Neonatal Respiratory Health Research, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, and Respiratory Support and Mechanisms.
Method for generating right ventricular pressure-volume loops in routine practice.
Loss of Y Chromosome Associates With Lung and Cardiac Dysfunction in COPD.
PVRI-GoDeep-A Global Meta-Registry at the Crossroads of Heart and Lung.
Diagnostic yield and histopathological assessment of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy: a prospective comparison of two tunnelling approaches.
Persistence of alveolar fibroblast-derived ADAMTS4+ cells in a preclinical model of delayed pulmonary fibrosis resolution.
FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis.
Assessment of pulmonary function in a mouse model of bronchopulmonary dysplasia by unrestrained whole body plethysmography and the forced oscillation technique.
Inhaled GM-CSF (Molgramostim) as host-directed therapy for pneumonia-related ARDS A multicenter, randomized, placebo-controlled phase 2a trial (GI-HOPE)
Mitochondrial COX4I2 drives pericyte-dependent inflammation and emphysema
Evidence for a lipofibroblast-to-<i>Cthrc1</i> <sup>+</sup> myofibroblast reversible switch during the development and resolution of lung fibrosis in young mice.
Rationale and design of the Renal Lifecycle trial assessing the effect of dapagliflozin on cardiorenal outcomes in severe chronic kidney disease
Rationale and design of the Renal Lifecycle trial assessing the effect of dapagliflozin on cardiorenal outcomes in severe chronic kidney disease.
Unraveling Alveolar Fibroblast and Activated Myofibroblast Heterogeneity and Differentiation Trajectories During Lung Fibrosis Development and Resolution in Young and Old Mice.
Association of Phosphodiesterase-5 Inhibitor Treatment With Improved Survival in Pulmonary Hypertension Associated With COPD in the Pulmonary Vascular Research Institute GoDeep Meta-Registry.
Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in Pulmonary Hypertension in Interstitial Lung Disease: A PVRI GoDeep Meta-Registry Analysis
Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury.
Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch.
Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery.
Living human lung slices for ex vivo modelling of lung cancer.
SPARCL1 and NT-proBNP as biomarkers of right ventricular-to-pulmonary artery uncoupling in pulmonary hypertension.
Living human lung slices for ex vivo modelling of lung cancer
Exercise haemodynamics in pulmonary hypertension - a prospective pressure-volume loop study on right ventricular adaptation and prognosis.
BDNF-TrkB Signaling Maintains Alveolar Epithelial Type 2 Cell Survival and Is Blocked in Hyperoxia-induced Neonatal Lung Injury.
Diffusion capacity and static hyperinflation as markers of disease progression predict 3-year mortality in COPD: Results from COSYCONET.
Acute Hemodynamic Effects of Sotatercept.
Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in Pulmonary Hypertension in Interstitial Lung Disease: A PVRI GoDeep Meta-Registry Analysis.
Survival Outcomes and Impact of Targeted PAH Therapy in Portopulmonary Hypertension in the PVRI GoDeep Meta-Registry.
Male survival disadvantage in pulmonary hypertension: independent of aetiology, age, disease severity, comorbidities and treatment
Death-associated protein kinase 1 prevents hypoxia-induced metabolic shift and pulmonary arterial smooth muscle cell proliferation in PAH.
Targeting IL6-Edn1-FoxO1 axis enables lung growth in mechanically ventilated newborn mice.