Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Cellular transport and secretion, Endoplasmic Reticulum Stress and Disease, Fungal and yeast genetics research, and Lipid Membrane Structure and Behavior.
Extracellular Vesicles and Cellular Homeostasis
Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair
p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes
Mechanism-guided engineering of a minimal biological particle for genome editing
Intercellular transmission of alpha-synuclein
Proteins that carry dual targeting signals can act as tethers between peroxisomes and partner organelles
Characterization of the interaction between the Sec61 translocon complex and ppαF using optical tweezers
Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair
Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein
The Secrets of Secretion: Protein Transport in Cells
From policy to practice: Lessons learned from an open science funding initiative
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1
Assembly of γ-secretase occurs through stable dimers after exit from the endoplasmic reticulum
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer
Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly
Buoyant Density Fractionation of Small Extracellular Vesicle Sub-populations Derived from Mammalian Cells
Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex
New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells
TANGO1 and SEC12 are copackaged with procollagen I to facilitate the generation of large COPII carriers
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
Remodeling of ER‐exit sites initiates a membrane supply pathway for autophagosome biogenesis
COPII-coated membranes function as transport carriers of intracellular procollagen I
Unconventional secretion of FABP4 by endosomes and secretory lysosomes
TFG facilitates outer coat disassembly on COPII transport carriers to promote tethering and fusion with ER–Golgi intermediate compartments
Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER–Golgi intermediate compartment
Cell-free Generation of COPII-coated Procollagen I Carriers