Area of research
Computer Graphics and Computer-Aided Design · Information Systems
Research interest
Research topics from publications: Optofluidic marine phosphate detection with enhanced absorption using a Fabry–Pérot resonator; Real-time detection and monitoring of the drug resistance of single myeloid leukemia cells by diffused total internal reflection. Representative work: An optofluidic phosphate analysis chip combined with a resonator has been created with enhanced absorption and real-time monitoring. It overcomes the obstacles of traditional methods with macroscale absorption cells, and low representative and time-sensitive detection results Real-time detection and monitoring of the drug resistance of single cells have important significance in clinical diagnosis and therapy. Traditional methods operate a number of times for each individual concentration, and innovation is required for the design of more simple and efficient manipulation platforms with necessary higher sensitivity. Here, we have developed a novel diffused total internal reflection (TIR) method to perform drug metabolism and cytotoxicity analysis of trapped myeloid leukemia cells. Molm-13 cells, a type of acute myeloid leukemia cell, were chosen and injected into the device and fittingly captured by cell traps. Differing from previous studies, a series of differe