Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Autophagy in Disease and Therapy, Mitochondrial Function and Pathology, Cancer Research and Treatments, and Cell death mechanisms and regulation.
Author Correction: PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury.
The X-Age Project to construct a Chinese aging clock
HnRNPA2B1 promotes cardiac ferroptosis via m6A-dependent stabilization of PFN2 mRNA in myocardial ischemia-reperfusion injury
BefA protein alleviates progression of non-alcoholic fatty liver disease by modulating the AMPK signaling pathway through the gut-liver axis
Sweetening ferroptosis spread.
NRF1-mediated innate immune response drives inflammaging.
Optimizing the Banking and Releasing Strategies of Clinical‐Grade HLA‐Homozygous Human iPSCs for Regenerative Medicine
Ferroptosis in health and disease
Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance.
PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury.
A Self‐Gelling Powder Directly Co‐Assembled by Natural Small Molecules for Traumatic Brain Injury
Stapled peptides: targeting protein-protein interactions in drug development
Zscan4 mediates ubiquitination and degradation of the corepressor complex to promote chromatin accessibility in 2C-like cells.
Author Correction: PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury.
Apoptotic cell death in disease—Current understanding of the NCCD 2023
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity.
O-GlcNAcylation regulates phagocytosis by promoting Ezrin localization at the cell cortex
Integration of FUNDC1-associated mitochondrial protein import and mitochondrial quality control contributes to TDP-43 degradation.
Publisher Correction: Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
Mitochondrial outer membrane protein FUNDC2 promotes ferroptosis and contributes to doxorubicin-induced cardiomyopathy.
Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms
LGR4 cooperates with PrPc to endow the stemness of colorectal cancer stem cells contributing to tumorigenesis and liver metastasis.
Mitophagy receptor FUNDC1 is regulated by PGC-1α/NRF1 to fine tune mitochondrial homeostasis.
PDCD4 Simultaneously Promotes Microglia Activation via PDCD4–MAPK–NF-κB Positive Loop and Facilitates Neuron Apoptosis During Neuroinflammation
Receptor-mediated mitophagy regulates EPO production and protects against renal anemia.
Upregulation of miR-216a-5p by Lentinan Targeted Inhibition of JAK2/STAT3 Signaling Pathway to Reduce Lung Adenocarcinoma Cell Stemness, Promote Apoptosis, and Slow Down the Lung Adenocarcinoma Mechanisms
Mitophagy, Mitochondrial Homeostasis, and Cell Fate