Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cell biology, Chemistry, Biology, Deubiquitinating enzyme, Ubiquitin, and Computational biology.
Discovery and characterization of potent macrocycle inhibitors of ubiquitin-specific protease-7
Targeted degradation via direct 26S proteasome recruitment
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation
Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions
Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation
Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46