Area of research
Biochemistry · Molecular Biology
Research interest
Research interests include Chemistry, Biochemistry, Biology, Demethylase, Cofactor, and Mycobacterium tuberculosis.
UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors
Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid Inhibitors
AI is a viable alternative to high throughput screening: a 318-target study
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1
An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across Biomembranes—Similar Vehicle, Different Destination
On the mechanism of calcium‐dependent activation of NADPH oxidase 5 (NOX5)
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction
Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing
MCM5: a new actor in the link between DNA replication and Meier-Gorlin syndrome
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors
Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase
Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation
Expanding the Druggable Space of the LSD1/CoREST Epigenetic Target: New Potential Binding Regions for Drug-Like Molecules, Peptides, Protein Partners, and Chromatin
Structural Basis for Benzothiazinone-Mediated Killing of <i>Mycobacterium tuberculosis</i>
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis