Area of research
Physiology · Cell Biology
Research interest
Research interests include Lysosomal Storage Disorders Research, Cellular transport and secretion, Glycogen Storage Diseases and Myoclonus, and Trypanosoma species research and implications.
Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration
Pathomechanisms in the neuronal ceroid lipofuscinoses
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
Synergistic effects of treating the spinal cord and brain in CLN1 disease
Towards a new understanding of NCL pathogenesis
Intrathecal enzyme replacement therapy improves motor function and survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis
Immune cells perturb axons and impair neuronal survival in a mouse model of infantile neuronal ceroid lipofuscinosis
Partial Correction of the CNS Lysosomal Storage Defect in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis by Neonatal CNS Administration of an Adeno-Associated Virus Serotype rh.10 Vector Expressing the Human <i>CLN3</i> Gene