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Wim E. Hennink

Utrecht University · NL
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Area of research
Biomaterials · Molecular Biology
Research interest
Research interests include Materials science, Self-healing hydrogels, Chemistry, Drug delivery, Nanotechnology, and Micelle.
h-index
citations
15,082
works
186
NIH funding
primary concept
email

Recent publications

Multidrug micelles and sonopermeation for chemotherapy co-delivery to brain tumors
Journal of Controlled Release 2025cited by 15position: middledoi
Nanoparticle-in-Hydrogel Delivery System for the Sequential Release of Two Drugs
Pharmaceutics 2025cited by 8position: middledoi
Lipid nanoparticle-mediated messenger RNA delivery for ex vivo engineering of natural killer cells
Journal of Controlled Release 2023cited by 49position: middledoi
Thermo-responsive Diels-Alder stabilized hydrogels for ocular drug delivery of a corticosteroid and an anti-VEGF fab fragment
Journal of Controlled Release 2023cited by 43position: middledoi
Oral pretreatment with β-lactoglobulin derived peptide and CpG co-encapsulated in PLGA nanoparticles prior to sensitizations attenuates cow’s milk allergy development in mice
Frontiers in Immunology 2023cited by 21position: middledoi
Anionic polysaccharides for stabilization and sustained release of antimicrobial peptides
International Journal of Pharmaceutics 2023cited by 20position: middledoi
Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: impact of tumor stroma on penetration and efficacy
Drug Delivery and Translational Research 2023cited by 19position: middledoi
Thermosensitive Biodegradable Hydrogels for Local and Controlled Cerebral Delivery of Proteins: MRI-Based Monitoring of <i>In Vitro</i> and <i>In Vivo</i> Protein Release
ACS Biomaterials Science & Engineering 2023cited by 17position: middledoi
Tunable polymeric micelles for taxane and corticosteroid co-delivery
Drug Delivery and Translational Research 2023cited by 13position: middledoi
Effect of Polyplex Size on Penetration into Tumor Spheroids
Molecular Pharmaceutics 2023cited by 12position: middledoi
Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles
Advanced Science 2022cited by 63position: middledoi
Hyaluronic Acid-PEG-Based Diels–Alder<i>In Situ</i>Forming Hydrogels for Sustained Intraocular Delivery of Bevacizumab
Biomacromolecules 2022cited by 55position: middledoi
Utilizing in vitro drug release assays to predict in vivo drug retention in micelles
International Journal of Pharmaceutics 2022cited by 40position: middledoi
Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles
Advanced Drug Delivery Reviews 2022cited by 35position: middledoi
Self-Healing Thermosensitive Hydrogel for Sustained Release of Dexamethasone for Ocular Therapy
ACS Polymers Au 2022cited by 28position: middledoi
Utility of Intravenous Curcumin Nanodelivery Systems for Improving <i>In Vivo</i> Pharmacokinetics and Anticancer Pharmacodynamics
Molecular Pharmaceutics 2022cited by 25position: middledoi
The Impact of Nanobody Density on the Targeting Efficiency of PEGylated Liposomes
International Journal of Molecular Sciences 2022cited by 23position: middledoi
Tuning the size of all-HPMA polymeric micelles fabricated by solvent extraction
Journal of Controlled Release 2022cited by 20position: lastdoi
Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation
Biomacromolecules 2022cited by 10position: middledoi
Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic
Journal of Controlled Release 2021cited by 193position: lastdoi
<i>In Vitro</i> and <i>In Vivo</i> Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin
Molecular Pharmaceutics 2021cited by 55position: lastdoi
LCST polymers with UCST behavior
Soft Matter 2021cited by 35position: middledoi
Lyophilization stabilizes clinical‐stage core‐crosslinked polymeric micelles to overcome cold chain supply challenges
Biotechnology Journal 2021cited by 30position: middledoi
Hydrolytic (In)stability of Methacrylate Esters in Covalently Cross-Linked Hydrogels Based on Chondroitin Sulfate and Hyaluronic Acid Methacrylate
ACS Omega 2021cited by 23position: middledoi
New mixed matrix membrane for the removal of urea from dialysate solution
Separation and Purification Technology 2021cited by 22position: middledoi
Inhibition of cow’s milk allergy development in mice by oral delivery of β‐lactoglobulin‐derived peptides loaded PLGA nanoparticles is associated with systemic whey‐specific immune silencing
Clinical & Experimental Allergy 2021cited by 21position: middledoi
Molecular targets for anticancer therapies in companion animals and humans: what can we learn from each other?
Theranostics 2021cited by 19position: middledoi
Hyaluronic acid and chondroitin sulfate (meth)acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation
Biomaterials 2020cited by 227position: middledoi
Clinically established biodegradable long acting injectables: An industry perspective
Advanced Drug Delivery Reviews 2020cited by 151position: middledoi
Intravitreal hydrogels for sustained release of therapeutic proteins
Journal of Controlled Release 2020cited by 147position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Tina Vermonden · Utrecht University54 papers (2012–2025)Cornelus F. van Nostrum · Utrecht University47 papers (2012–2023)Twan Lammers · Utrecht University33 papers (2012–2025)Gert Storm · University of Applied Sciences Utrecht33 papers (2012–2025)Robbert J. Kok · Utrecht University22 papers (2012–2022)Fabian Kießling · Institute of Molecular Medicine20 papers (2013–2025)Raymond M. Schiffelers · Utrecht University18 papers (2012–2025)Enrico Mastrobattista · Utrecht University17 papers (2012–2023)Mies J. van Steenbergen · Utrecht University14 papers (2013–2022)Cristianne J.F. Rijcken · Utrecht University13 papers (2012–2022)Marcel H.A.M. Fens · Utrecht University10 papers (2014–2022)Maryam Amidi · Utrecht University9 papers (2012–2017)Sabrina Oliveira · Utrecht University9 papers (2012–2022)Josbert M. Metselaar · Utrecht University8 papers (2013–2025)Jos Malda · University of Applied Sciences Utrecht8 papers (2013–2017)Qizhi Hu · Nanjing Tech University7 papers (2015–2022)Ferry Ossendorp · Leiden University Medical Center7 papers (2014–2019) · 7 papers (2014–2018)Bo Lou · Utrecht University7 papers (2014–2020)Eduardo Ruiz‐Hernández · Utrecht University7 papers (2013–2020)
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