Area of research
Molecular Biology · Toxicology
Research interest
Research interests include Cancer research, Biology, Topoisomerase, DNA, RHEB, and PI3K/AKT/mTOR pathway.
Topoisomerases and cancer chemotherapy: recent advances and unanswered questions
DNA topoisomerase-targeting chemotherapeutics: what’s new?
Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes
Point mutations of the mTOR-RHEB pathway in renal cell carcinoma
DNA Topoisomerase I Domain Interactions Impact Enzyme Activity and Sensitivity to Camptothecin
Tyrosyl-DNA Phosphodiesterase I Catalytic Mutants Reveal an Alternative Nucleophile That Can Catalyze Substrate Cleavage
4-Hydroxytamoxifen Induces Autophagic Death through K-Ras Degradation
Development and Histopathological Characterization of Tumorgraft Models of Pancreatic Ductal Adenocarcinoma