Area of research
Molecular Biology · Oncology
Research interest
Research interests include Ubiquitin and proteasome pathways, Peptidase Inhibition and Analysis, Cancer, Hypoxia, and Metabolism, and Epigenetics and DNA Methylation.
Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Dual role of ER stress in response to metabolic co-targeting and radiosensitivity in head and neck cancer cells
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration
Molecular basis of USP7 inhibition by selective small-molecule inhibitors
PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes
Protein sequences bound to mineral surfaces persist into deep time
Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche
<scp>SCF</scp> (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
The why and how of amino acid analytics in cancer diagnostics and therapy
Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates
Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis
DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair
Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis
OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo
Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis
Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
German Version of ItchyQoL: Validation and Initial Clinical Findings
A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance
Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress
118 DEEP SEQUENCING OF THE PORCINE ENDOMETRIAL TRANSCRIPTOME ON DAYS 12 AND 14 OF PREGNANCY