Area of research
Molecular Biology
Research interest
Research interests include Developmental Biology and Gene Regulation, Angiogenesis and VEGF in Cancer, Cancer-related gene regulation, and Wnt/β-catenin signaling in development and cancer.
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
Notch signaling regulates UNC5B to suppress endothelial proliferation, migration, junction activity, and retinal plexus branching
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA
Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration
Inactivation of <i>Notch4</i> Attenuated Pancreatic Tumorigenesis in Mice
Release of stem cells from quiescence reveals gliogenic domains in the adult mouse brain
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking
Unique functions for Notch4 in murine embryonic lymphangiogenesis
CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function
Implications for preeclampsia: hypoxia-induced Notch promotes trophoblast migration
Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model
Extracellular Matrix Rigidity Modulates Human Cervical Smooth Muscle Contractility—New Insights into Premature Cervical Failure and Spontaneous Preterm Birth
Endothelial Jagged1 Antagonizes Dll4/Notch Signaling in Decidual Angiogenesis during Early Mouse Pregnancy
Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair
Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
Omega-3 fatty acids suppress Fusobacterium nucleatum–induced placental inflammation originating from maternal endothelial cells
Consensus guidelines for the use and interpretation of angiogenesis assays
Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence
Leukotriene B<sub>4</sub>antagonism ameliorates experimental lymphedema
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts
PDGFRβ-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis
NOTCH3 regulates stem-to–mural cell differentiation in infantile hemangioma
Dynamic maternal and fetal Notch activity and expression in placentation
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
A selective microRNA-based strategy inhibits restenosis while preserving endothelial function
Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis
Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia
Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization