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Roberto Hegg

Universidade de São Paulo · BR
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Advanced Breast Cancer Therapies, Breast Cancer Treatment Studies, HER2/EGFR in Cancer Research, and Cancer Treatment and Pharmacology.
h-index
40
citations
19,434
works
181
NIH funding
primary concept
Medicine
email

Recent publications

Sacituzumab Govitecan in Untreated, Advanced Triple-Negative Breast Cancer
New England Journal of Medicine 2025cited by 36position: middledoi
Peri-operative atezolizumab in early-stage triple-negative breast cancer: final results and ctDNA analyses from the randomized phase 3 IMpassion031 trial
Nature Medicine 2025cited by 24position: middledoi
Overall survival with abemaciclib in early breast cancer
Annals of Oncology 2025cited by 20position: middledoi
LBA1 Final analysis of the placebo-controlled randomised phase III IMpassion031 trial evaluating neoadjuvant atezolizumab (atezo) plus chemotherapy (CT) followed by open-label adjuvant atezo in patients (pts) with early-stage triple-negative breast cancer (eTNBC)
ESMO Open 2023cited by 25position: middledoi
Trastuzumab deruxtecan versus trastuzumab emtansine in patients with HER2-positive metastatic breast cancer: updated results from DESTINY-Breast03, a randomised, open-label, phase 3 trial
The Lancet 2022cited by 616position: middledoi
Abstract GS3-01: Trastuzumab deruxtecan (T-DXd; DS-8201a) vs. trastuzumab emtansine (T-DM1) in patients (pts) with HER2+ metastatic breast cancer (mBC): subgroup analyses from the randomized phase 3 study DESTINY-Breast03
Cancer Research 2022cited by 55position: middledoi
Primary results from IMpassion131, a double-blind, placebo-controlled, randomised phase III trial of first-line paclitaxel with or without atezolizumab for unresectable locally advanced/metastatic triple-negative breast cancer
Annals of Oncology 2021cited by 716position: middledoi
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
Annals of Oncology 2021cited by 374position: middledoi
Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: Updated Results of ALTERNATIVE.
2021cited by 92position: contributordoi
nextMONARCH: Abemaciclib Monotherapy or Combined With Tamoxifen for Metastatic Breast Cancer.
2021cited by 32position: contributordoi
FLABRA, frontline approach for <i>BRCA</i> testing in an ovarian cancer population: a Latin America epidemiologic study.
2021cited by 7position: contributordoi
Abstract PS13-25: Management of abemaciclib associated diarrhea in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: Analysis of the MONARCH plus study
Cancer Research 2021cited by 1position: middledoi
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial
The Lancet 2020cited by 1,776position: middledoi
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial.
2020cited by 1,364position: contributordoi
Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial
The Lancet 2020cited by 1,053position: middledoi
Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study
The Lancet Oncology 2020cited by 880position: middledoi
Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial.
2020cited by 782position: contributordoi
Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2-, Node-Positive, High-Risk, Early Breast Cancer (monarchE).
2020cited by 714position: contributordoi
Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study.
2020cited by 657position: contributordoi
Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial.
2020cited by 176position: contributordoi
MONARCH plus: abemaciclib plus endocrine therapy in women with HR+/HER2– advanced breast cancer: the multinational randomized phase III study
Therapeutic Advances in Medical Oncology 2020cited by 106position: middledoi
MONARCH plus: abemaciclib plus endocrine therapy in women with HR+/HER2- advanced breast cancer: the multinational randomized phase III study.
2020cited by 84position: contributordoi
LBA11 IMpassion031: Results from a phase III study of neoadjuvant (neoadj) atezolizumab + chemotherapy in early triple-negative breast cancer (TNBC)
Annals of Oncology 2020cited by 28position: middledoi
Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer.
2019cited by 507position: contributordoi
Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial
The Lancet Oncology 2019cited by 253position: middledoi
Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE).
2019cited by 82position: contributordoi
Subcutaneous vs Intravenous Trastuzumab for Patients With ERBB2-Positive Early Breast Cancer: Final Analysis of the HannaH Phase 3 Randomized Clinical Trial.
2019cited by 60position: contributordoi
Randomized phase II study evaluating weekly oral vinorelbine versus weekly paclitaxel in estrogen receptor-positive, HER2-negative patients with advanced breast cancer (NorBreast-231 trial).
2019cited by 10position: contributordoi
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
New England Journal of Medicine 2018cited by 4,325position: middledoi
Everolimus Plus Endocrine Therapy for Postmenopausal Women With Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer
JAMA Oncology 2018cited by 68position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Joohyuk Sohn · Fudan University Shanghai Cancer Center9 papers (2019–2025)Nadia Harbeck · Universität Bayern6 papers (2012–2025)Carlos H. Barrios · Centro Brasileiro de Estudos em Dermatologia6 papers (2018–2025)Hiroji Iwata · Juntendo University6 papers (2018–2023)Kevin Punie · Ziekenhuisnetwerk Antwerpen Stuivenberg5 papers (2020–2025)Luciana Molinero · Hospital Clínic de Barcelona5 papers (2018–2025)Shigehira Saji · Fukushima Medical University Hospital4 papers (2020–2025)Javier Cortés · Universidade Nova de Lisboa4 papers (2013–2025)Andreas Koehler · University of North Carolina at Chapel Hill4 papers (2020–2025)Erika Hamilton · Duke Medical Center4 papers (2020–2025)Kyung Hae Jung · Ulsan College3 papers (2020–2025)Melinda L. Telli · Stanford University3 papers (2020–2025)Jane Yuet Ching Hui · University of Minnesota3 papers (2018–2025)Cristiano Ferrario · Institut Claudius Regaud3 papers (2020–2025)Bohuslav Melichar · Cancer Research UK3 papers (2019–2020)Sherene Loi · Peter MacCallum Cancer Centre3 papers (2018–2020)Mario Liste-Hermoso · Roche (Switzerland)3 papers (2020–2025)Shilpen Patel · AbbVie (United States)2 papers (2020–2020)Stephen Johnston · Royal Marsden NHS Foundation Trust2 papers (2020–2021)Luís Teixeira · Inserm2 papers (2019–2020)