Area of research
Molecular Biology
Research interest
Research interests include Ubiquitin ligase, Biology, Wnt signaling pathway, Cell biology, Cancer research, and Ubiquitin.
The pathogenic factor of ZC4H2-associated rare disorder is a postsynaptic regulator for synaptic activity and cognitive function
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation
RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission
ZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation
Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression
Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning
ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling
Satb2 is required for the regionalization of retrosplenial cortex
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth
Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation
The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of β-Catenin
Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells
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