Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cell death mechanisms and regulation, Protein Degradation and Inhibitors, Sarcoma Diagnosis and Treatment, and Acute Myeloid Leukemia Research.
Menin-inhibition boosts CAR-T cell therapy against NPM1 mutated and KMT2A-rearranged acute myeloid leukemia
Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with <i>MLL</i> rearrangement or <i>NPM1</i> mutation to venetoclax
Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines
The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells
Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells
Targeting ferroptosis in rhabdomyosarcoma cells
<i>NRAS</i> -Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3K <b>α</b>
Rhabdomyosarcoma cells are susceptible to cell death by LDK378 alone or in combination with sorafenib independently of anaplastic lymphoma kinase status