Area of research
Immunology · Molecular Biology
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Gut microbiota and health, and Probiotics and Fermented Foods.
Commensal microbe-derived butyrate enhances T follicular helper cell function to boost mucosal vaccine efficacy.
Conserved noncoding sequence-9 regulates NFATc1-mediated IL-10 expression in B cells to control inflammatory responses.
Beyond the gut: decoding the gut-immune-brain axis in health and disease.
Gut microbiota in regulatory T cell generation and function: mechanisms and health implications.
Gut microbiota and brain-resident CD4<sup>+</sup> T cells shape behavioral outcomes in autism spectrum disorder.
A Co-essentiality Network of Cancer Driver Genes Better Prioritizes Anticancer Drugs.
A dietary commensal microbe enhances antitumor immunity by activating tumor macrophages to sequester iron.
Cell-cell communication network-based interpretable machine learning predicts cancer patient response to immune checkpoint inhibitors.
Probiotic Consortium Confers Synergistic Anti-Inflammatory Effects in Inflammatory Disorders.
Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells.
ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression.
Gut Microbiota Defines Functional Direction of Colonic Regulatory T Cells with Unique TCR Repertoires.
IL2-mediated modulation of small extracellular vesicles secretion and PD-L1 expression: a novel perspective for neutralizing immune suppression within cancer cells.
A Co-essentiality Network of Cancer Driver Genes Better Prioritizes Anticancer Drugs
Exploring probiotic effector molecules and their mode of action in gut-immune interactions.
The transcription factor Mef2d regulates B:T synapse-dependent GC-T<sub>FH</sub> differentiation and IL-21-mediated humoral immunity.
Forkhead box protein D2 suppresses colorectal cancer by reprogramming enhancer interactions.
Microbial Components and Effector Molecules in T Helper Cell Differentiation and Function.
Network-based machine learning approach to predict immunotherapy response in cancer patients.
ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts.
Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target.
NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages.
T Helper 2-Associated Immunity in the Pathogenesis of Systemic Lupus Erythematosus.
Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays.
Drug approval prediction based on the discrepancy between gene perturbation effects in cells and humans
Ribociclib plus fulvestrant for postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in the phase III randomized MONALEESA-3 trial: updated overall survival
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities.
Commensal Microbiome Expands Tγδ17 Cells in the Lung and Promotes Particulate Matter-Induced Acute Neutrophilia.
Probiotics-derived metabolite ameliorates skin allergy by promoting differentiation of FOXP3<sup>+</sup> regulatory T cells.
<i>Listeria monocytogenes</i> Establishes Commensalism in Germ-Free Mice Through the Reversible Downregulation of Virulence Gene Expression.