Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Parkinson's Disease Mechanisms and Treatments, and Prion Diseases and Protein Misfolding.
Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer’s disease
Particulate matter and co-occurring genetic risk induce oxidative stress and cardiac and brain Alzheimer’s pathology
Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis
Tau induces formation of α-synuclein filaments with distinct molecular conformations
Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau
Untwisted α-synuclein Filaments formed in the Presence of Lipid Vesicles
Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons
Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspective
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies
Tau oligomers in cerebrospinal fluid in Alzheimer's disease
A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1
Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies
Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice