Area of research
Immunology · Transplantation
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and Renal Transplantation Outcomes and Treatments.
The inflammaging microenvironment induces dysfunctional rewiring of Tfh cell differentiation
Transplanting old organs promotes senescence in young recipients
IL-21–producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice
Transcriptionally Distinct B Cells Infiltrate Allografts After Kidney Transplantation
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses
FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program
DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation
Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation
T follicular regulatory cells
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
T follicular regulatory cells in the regulation of B cell responses
Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity
The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells
Circulating T follicular regulatory and helper cells have memory-like properties
Response to BRAF Inhibition in Melanoma Is Enhanced When Combined with Immune Checkpoint Blockade
The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood