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Jeffrey L. Franklin

University of Notre Dame · GB
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Extracellular vesicles in disease, MicroRNA in disease regulation, RNA Research and Splicing, and RNA modifications and cancer.
h-index
39
citations
11,398
works
114
NIH funding
primary concept
Biology
email

Recent publications

EGFR S442 ectodomain mutation confers cetuximab resistance that can be overcome by ERBB2 blockade with trastuzumab-deruxtecan
Cancer Letters 2026cited by 0position: contributordoi
A comprehensive analysis of supermere, exomere, and extracellular vesicle isolation and cargo in colorectal cancer
Cell Reports 2025cited by 4position: contributordoi
Comparison of EV characterization by commercial high‐sensitivity flow cytometers and a custom single‐molecule flow cytometer
Journal of Extracellular Vesicles 2024cited by 39position: middledoi
The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research
Extracellular Vesicle 2024cited by 4position: contributordoi
Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research
iScience 2022cited by 30position: middledoi
Additional file 3 of Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression
Open MIND 2022cited by 0position: middledoi
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Nature Cell Biology 2021cited by 397position: middledoi
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
Cell 2021cited by 332position: middledoi
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
2021cited by 262position: contributordoi
Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences
Heliyon 2021cited by 17position: contributordoi
Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors
2021cited by 2position: contributordoi
Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells.
2020cited by 43position: contributordoi
Reassessment of Exosome Composition
Cell 2019cited by 2,912position: middledoi
Transfer of Functional Cargo in Exomeres
Cell Reports 2019cited by 377position: middledoi
The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research
Cell 2019cited by 225position: middledoi
Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs.
2019cited by 92position: contributordoi
Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation.
2019cited by 8position: contributordoi
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling
Nature Medicine 2017cited by 452position: middledoi
Biogenesis, delivery, and function of extracellular RNA
Journal of Extracellular Vesicles 2015cited by 96position: middledoi
The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
Cell 2012cited by 688position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 8 papers (2019–2026)Robert J. Coffey · Vanderbilt University5 papers (2012–2019)Robert J. Coffey · Shared Spectrum Company (United States)4 papers (2019–2025)Alissa M. Weaver · Vanderbilt University3 papers (2015–2021) · 3 papers (2015–2019)Qi Liu · Ruijin Hospital3 papers (2017–2019)James N. Higginbotham · University of Notre Dame3 papers (2012–2019)Kasey C. Vickers · Vanderbilt University2 papers (2015–2019) · 2 papers (2017–2019)Jie Ping · Shanghai Medical College of Fudan University2 papers (2019–2019)Qin Zhang · Shanghai University2 papers (2019–2019)Kasey C. Vickers · Vanderbilt University2 papers (2021–2025) · 2 papers (2019–2021) · 2 papers (2019–2021) · 2 papers (2019–2021)Bhuminder Singh · Iowa State University2 papers (2019–2026) · 2 papers (2019–2019)James R. Goldenring · Vanderbilt University2 papers (2019–2021)Anna L. Means · Vanderbilt University Medical Center1 papers (2012–2012)Bo Huang · Jiujiang University1 papers (2015–2015)