Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cancer-related Molecular Pathways, Epigenetics and DNA Methylation, Telomeres, Telomerase, and Senescence, and RNA modifications and cancer.
Disruption of ataxia telangiectasia–mutated kinase enhances radiation therapy efficacy in spatially directed diffuse midline glioma models
p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice
Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
The Mettl3 epitranscriptomic writer amplifies p53 stress responses
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies
Specifications of the ACMG/AMP variant interpretation guidelines for germline <i>TP53</i> variants
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes
Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders
A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Unravelling mechanisms of p53-mediated tumour suppression