Area of research
Atmospheric Science · Surgery
Research interest
Research topics from publications: Peptide codes for organ-selective mRNA delivery; Multi‐Scale Ice Inhibition Platform Enables Full‐Cycle Cryogenic Protection for Mouse Oocyte; Human gastroids to model regional patterning in early stomach development. Representative work: Abstract Cryopreservation of metaphase II (MII) oocytes is crucial to preserve female fertility. However, the existing vitrification technology just provides partial cryogenic protection for oocytes and must use high concentrations of toxic penetrating cryoprotective agents (CPAs, up to 4.8 M). Here, a multi‐scale ice inhibition platform is proposed, which effectively suppresses ice crystal morphology, ice recrystallization (IR), temperature gradient, and devitrification. This platform achieves mouse oocyte survival rate of 98.6% using the low concentration of CPA (3.1 M) while also possessing batch oocyte cryopreservation ability. In contrast, recovered oocytes show a much more modest varia