Area of research
Molecular Biology · Immunology
Research interest
Research interests include Cancer research, Biology, Downregulation and upregulation, Carcinogenesis, Gene knockdown, and Cell growth.
ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation
Exposure to blue light stimulates the proangiogenic capability of exosomes derived from human umbilical cord mesenchymal stem cells
Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes
Aryl hydrocarbon receptor (AhR) regulates adipocyte differentiation by assembling CRL4B ubiquitin ligase to target PPARγ for proteasomal degradation
Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer
Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition
Dysregulation of the miR‐194–<scp>CUL</scp>4B negative feedback loop drives tumorigenesis in non‐small‐cell lung carcinoma
A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions
GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment
Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation
MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C
miR-155 Deficiency Ameliorates Autoimmune Inflammation of Systemic Lupus Erythematosus by Targeting <i>S1pr1</i> in <i>Faslpr/lpr</i> Mice
Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51
The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment
Berberine Induces Senescence of Human Glioblastoma Cells by Downregulating the EGFR–MEK–ERK Signaling Pathway
CUL4B activates Wnt/β‐catenin signalling in hepatocellular carcinoma by repressing Wnt antagonists
CRL4B interacts and coordinates with SIN3A/HDAC complex to repress <i>CDKN1A</i> in driving cell cycle progression
CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing
CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis
<i>MiR‐182</i> overexpression in tumourigenesis of high‐grade serous ovarian carcinoma
Zinc Fingers and Homeoboxes 2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Represses Expression of Cyclins A and E