Area of research
Immunology · Molecular Biology
Research interest
Research interests include Single-cell and spatial transcriptomics, Cell Image Analysis Techniques, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses.
FIP200 regulates plasma B cell differentiation via mitochondrial and heme homeostasis.
Intra-articular injection of autologous tolerogenic dendritic cells modifies the synovial immune landscape in rheumatoid and inflammatory arthritis
Flow cytometry-based isolation of
<i>Salmonella</i>
-containing phagosomes combined with ultra-sensitive proteomics reveals novel insights into host-pathogen interactions
A prenatal skin atlas reveals immune regulation of human skin morphogenesis
A prenatal skin atlas reveals immune regulation of human skin morphogenesis.
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission.
OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration.
A novel channel invariant architecture for the segmentation of cells and nuclei in multiplexed images using InstanSeg
A multi-biomarker micronucleus assay using imaging flow cytometry
Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19.
Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration.
SCIP: A scalable, reproducible and open-source pipeline for morphological profiling of image cytometry and microscopy data.
Guidelines for establishing a cytometry laboratory.
A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders.
A multi-biomarker micronucleus assay using imaging flow cytometry.
Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis
<i>Ex-vivo</i> mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screening
Protocol for in vitro co-culture, proliferation, and cell cycle analyses of patient-derived leukemia cells.
Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis
Parkinson's disease neurons exhibit alterations in mitochondrial quality control proteins.
Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis.
GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data.
Programmed cell death-1 receptor-mediated regulation of Tbet<sup>+</sup>NK1.1<sup>-</sup> innate lymphoid cells within the tumor microenvironment.
<scp>OPTIMAL</scp> : An <scp>OPTimized</scp> Imaging Mass cytometry <scp>AnaLysis</scp> framework for benchmarking segmentation and data exploration
Downregulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19.
Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia.
Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19
OPTIMAL: An OPTimised Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration
Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19
Identification of a protein expression signature distinguishing early from organising diffuse alveolar damage in COVID-19 patients.