Area of research
Virology · Infectious Diseases
Research interest
Research interests include HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, HIV/AIDS drug development and treatment, and Immune Cell Function and Interaction.
HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors
Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia
A Protective Role for the Lectin CD169/Siglec-1 During SARS-CoV-2 Infection
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET
Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice
Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice
HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations
HIV-1-Infected CD4+ T Cells Facilitate Latent Infection of Resting CD4+ T Cells through Cell-Cell Contact
The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins
Proceedings of the Frontiers of Retrovirology Conference 2016
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
Video-rate nanoscopy using sCMOS camera–specific single-molecule localization algorithms
TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity