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Walther Mothes

Yale University · US
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Area of research
Virology · Infectious Diseases
Research interest
Research interests include HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, HIV/AIDS drug development and treatment, and Immune Cell Function and Interaction.
h-index
57
citations
15,340
works
195
NIH funding
primary concept
email

Recent publications

HKU5 bat merbecoviruses engage bat and mink ACE2 as entry receptors
Nature Communications 2025cited by 5position: middledoi
Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging
Cell chemical biology 2024cited by 15position: middledoi
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
Nature 2023cited by 93position: middledoi
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry
Nature Communications 2023cited by 37position: middledoi
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia
The Journal of Infectious Diseases 2023cited by 27position: middledoi
A Protective Role for the Lectin CD169/Siglec-1 During SARS-CoV-2 Infection
SSRN Electronic Journal 2023cited by 0position: middledoi
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
Cell Host & Microbe 2021cited by 208position: middledoi
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy
SSRN Electronic Journal 2021cited by 9position: middledoi
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements
Nature Communications 2020cited by 59position: middledoi
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins
Journal of Virology 2020cited by 47position: middledoi
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET
Nature 2019cited by 216position: lastdoi
Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice
PLoS Pathogens 2019cited by 26position: lastdoi
Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice
Journal of Virology 2019cited by 10position: middledoi
HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations
eLife 2018cited by 167position: lastdoi
HIV-1-Infected CD4+ T Cells Facilitate Latent Infection of Resting CD4+ T Cells through Cell-Cell Contact
Cell Reports 2018cited by 81position: middledoi
The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Nature Communications 2017cited by 115position: middledoi
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
Science 2016cited by 377position: middledoi
Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins
mBio 2016cited by 172position: middledoi
Proceedings of the Frontiers of Retrovirology Conference 2016
Retrovirology 2016cited by 37position: middledoi
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Nature Structural & Molecular Biology 2015cited by 368position: middledoi
HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy
Trends in Microbiology 2015cited by 110position: lastdoi
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
Nature 2014cited by 772position: middledoi
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
Science 2014cited by 527position: lastdoi
Video-rate nanoscopy using sCMOS camera–specific single-molecule localization algorithms
Nature Methods 2013cited by 560position: middledoi
TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity
Journal of Virology 2012cited by 217position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

· 8 papers (2012–2023)Scott C. Blanchard · St. Jude Children's Research Hospital6 papers (2014–2020) · 5 papers (2018–2024)Peter D. Kwong · National Institutes of Health4 papers (2014–2024)Amos B. Smith · California University of Pennsylvania4 papers (2014–2020) · 4 papers (2020–2024)Xiaochu Ma · University of Maryland, College Park4 papers (2014–2018)James B. Munro · Uniformed Services University of the Health Sciences3 papers (2014–2018)Joseph Sodroski · Harvard University3 papers (2016–2020)James Arthos · New York University3 papers (2014–2024)Joerg Bewersdorf · Yale University2 papers (2013–2023)Cameron F. Abrams · Drexel University2 papers (2017–2020)Collin Kieffer · University of Illinois Urbana-Champaign2 papers (2019–2023)Luis M. Agosto · Editas Medicine (United States)2 papers (2015–2018)John D. Ventura · Beth Israel Deaconess Medical Center2 papers (2016–2019)Andrés Finzi · McGill University2 papers (2016–2023)Mark P. Farrell · Indiana University – Purdue University Indianapolis2 papers (2017–2020)Alon Herschhorn · University of Minnesota, Twin Cities2 papers (2016–2017) · 2 papers (2019–2023)Zhou Zhou · Hebei Medical University2 papers (2014–2018)
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