Jeffrey J. Widrick

Muscle-specific increased expression of <i>JAG1</i> improves skeletal muscle phenotype in dystrophin-deficient mice

Identifying kinematic biomarkers of the dystrophic phenotype in a zebrafish model of Duchenne muscular dystrophy.

Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior.

Conditional <i>Dystrophin</i> ablation in the skeletal muscle and brain causes profound effects on muscle function, neurobehavior, and extracellular matrix pathways

High resolution kinematic approach for quantifying impaired mobility of dystrophic zebrafish larvae

Optimizing assays of zebrafish larvae swimming performance for drug discovery.

DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism.

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.

Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.

Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species

Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function

Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens

The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes

SPEG-deficient skeletal muscles exhibit abnormal triad and defective calcium handling

A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

Lack of Neuromuscular Origins of Adaptation After a Long-Term Stretching Program