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John Bowes

University of Manchester · GB
Area of research
Rheumatology · Hematology
Research interest
Research interests include Biology, Genome-wide association study, Genetics, Medicine, Genotyping, and Rheumatoid arthritis.
h-index
citations
5,850
works
27
NIH funding
primary concept
email

Recent publications

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nature Communications 2025cited by 53position: middledoi
10-year multimorbidity patterns among people with and without rheumatic and musculoskeletal diseases: an observational cohort study using linked electronic health records from Wales, UK
BMJ Open 2024cited by 2position: middledoi
EULAR study group on ‘MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders
Annals of the Rheumatic Diseases 2023cited by 74position: middledoi
A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs
Cell Genomics 2023cited by 14position: middledoi
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
Nature Genetics 2022cited by 340position: middledoi
Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling
Arthritis & Rheumatology 2022cited by 47position: middledoi
Association with HLA-DRβ1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis
Human Molecular Genetics 2022cited by 28position: middledoi
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
Nature Genetics 2021cited by 67position: middledoi
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms
Annals of the Rheumatic Diseases 2020cited by 86position: lastdoi
Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups
Annals of the Rheumatic Diseases 2019cited by 120position: middledoi
Brief Report: The Genetic Profile of Rheumatoid Factor–Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis
Arthritis & Rheumatology 2018cited by 67position: middledoi
Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis
Annals of the Rheumatic Diseases 2017cited by 71position: firstdoi
Immune‐Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA–DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum
Arthritis & Rheumatology 2017cited by 62position: middledoi
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Annals of the Rheumatic Diseases 2016cited by 163position: middledoi
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases
Annals of the Rheumatic Diseases 2016cited by 121position: middledoi
Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
Nature Communications 2015cited by 185position: firstdoi
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits
PLoS ONE 2015cited by 152position: middledoi
PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus
Annals of the Rheumatic Diseases 2015cited by 82position: firstdoi
Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
The American Journal of Human Genetics 2014cited by 177position: middledoi
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
Annals of the Rheumatic Diseases 2014cited by 117position: middledoi
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Nature 2013cited by 2,460position: middledoi
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
Nature Genetics 2013cited by 412position: middledoi
Variants in <i>RUNX3</i> Contribute to Susceptibility to Psoriatic Arthritis, Exhibiting Further Common Ground With Ankylosing Spondylitis
Arthritis & Rheumatism 2013cited by 69position: middledoi
Brief Report: Identification of <i>BACH2</i> and <i>RAD51B</i> as Rheumatoid Arthritis Susceptibility Loci in a Meta‐Analysis of Genome‐Wide Data
Arthritis & Rheumatism 2013cited by 57position: middledoi
Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
PLoS Genetics 2013cited by 56position: middledoi
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
Nature Genetics 2012cited by 675position: middledoi
Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis
The American Journal of Human Genetics 2012cited by 93position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anne Barton · University of Manchester4 papers (2013–2024)Stephen Eyre · University of Manchester3 papers (2013–2022)Annie Yarwood · University of Manchester2 papers (2013–2020)Marie Feletar · Monash University2 papers (2015–2017)Carl D. Langefeld · Winston-Salem State University2 papers (2020–2023)Eleanor Korendowych · AbbVie (United States)2 papers (2015–2017) · 2 papers (2015–2017)Dorothée Diogo · Massachusetts Institute of Technology2 papers (2013–2014)Philip Helliwell · University of Leeds2 papers (2015–2017)Helena Marzo‐Ortega · University of Leeds2 papers (2015–2017)Jon Packham · University of Nottingham2 papers (2015–2017)Pauline Ho · University of Manchester2 papers (2015–2017)Lars Klareskog · Karolinska University Hospital2 papers (2013–2014)Neil McHugh · Royal National Hospital for Rheumatic Diseases2 papers (2015–2017)Farideh Jalalinajafabadi · University of Manchester2 papers (2017–2024)Oliver FitzGerald · University College Dublin2 papers (2015–2017)Soumya Raychaudhuri · Broad Institute2 papers (2014–2022)Peter K. Gregersen · Northwell Health2 papers (2013–2014)Gisela Orozco · University of Manchester2 papers (2013–2020)Jane Worthington · University of Manchester2 papers (2013–2014)