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Karl A. Merrick

Massachusetts Institute of Technology · US
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Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, Epigenetics and DNA Methylation, and DNA Repair Mechanisms.
h-index
13
citations
1,165
works
25
NIH funding
primary concept
email

Recent publications

An RNA damage response network mediates the lethality of 5-FU in colorectal cancer
Cell Reports Medicine 2024cited by 37position: middledoi
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
Bioorganic & Medicinal Chemistry Letters 2019cited by 64position: middledoi
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis
Proceedings of the National Academy of Sciences 2018cited by 115position: middledoi
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy
Cancer Cell 2015cited by 95position: middledoi
A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression
Molecular Cell 2013cited by 173position: middledoi
Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways
Proceedings of the National Academy of Sciences 2012cited by 75position: middledoi
Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells
PLoS Genetics 2012cited by 60position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michael B. Yaffe · Beth Israel Deaconess Medical Center3 papers (2015–2024)Kevan M. Shokat · Howard Hughes Medical Institute3 papers (2012–2013)Robert P. Fisher · Icahn School of Medicine at Mount Sinai3 papers (2012–2013)Ian G. Cannell · University of Cambridge2 papers (2015–2024)Stéphane Larochelle · Université Laval2 papers (2012–2013)Sandra Morandell · Massachusetts Institute of Technology2 papers (2015–2018) · 2 papers (2012–2012)Yi Wen Kong · Massachusetts Institute of Technology2 papers (2018–2024)Lucía Suárez-López · Massachusetts Institute of Technology2 papers (2018–2024)Chao Zhang · Ministry of Public Security of the People's Republic of China2 papers (2012–2012)Leonard Kusdra · Kantar Health (United States)1 papers (2012–2012)Erika D. Handly · Massachusetts Institute of Technology1 papers (2024–2024)Dai Horiuchi · Chiba University1 papers (2012–2012)Seth M. Rubin · University of California, Santa Cruz1 papers (2013–2013)Ramon Amat · Hebron University1 papers (2012–2012)Jonathan M. Hernandez · National Institutes of Health1 papers (2024–2024)Christian Braun · LMU Klinikum1 papers (2015–2015)Kevin M. Haigis · Brigham and Women's Hospital1 papers (2018–2018)George Eng · Massachusetts Institute of Technology1 papers (2024–2024)Saurav De · Northwell Health1 papers (2012–2012)
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