Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, Epigenetics and DNA Methylation, and DNA Repair Mechanisms.
An RNA damage response network mediates the lethality of 5-FU in colorectal cancer
Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy
A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression
Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways
Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells