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Yuri Rukazenkov

AstraZeneca (United Kingdom) · GB
🔎 Find collaborators in Pulmonary and Respiratory Medicine · Oncology →
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Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Lung Cancer Treatments and Mutations, Lung Cancer Diagnosis and Treatment, Colorectal Cancer Treatments and Studies, and Lung Cancer Research Studies.
h-index
30
citations
16,717
works
91
NIH funding
primary concept
Osimertinib
email

Recent publications

Neoadjuvant Osimertinib for Resectable <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer
Journal of Clinical Oncology 2025cited by 49position: middledoi
Molecular residual disease analysis of adjuvant osimertinib in resected EGFR-mutated stage IB–IIIA non-small-cell lung cancer
Nature Medicine 2025cited by 38position: middledoi
A plain language summary of results from the FLAURA2 study: Initial (first-line) osimertinib treatment with or without chemotherapy in patients with untreated EGFR-mutated advanced NSCLC
Future Oncology 2025cited by 1position: middledoi
Molecular residual disease (MRD) analysis from the ADAURA trial of adjuvant (adj) osimertinib in patients (pts) with resected EGFR-mutated (EGFRm) stage IB–IIIA non-small cell lung cancer (NSCLC).
Journal of Clinical Oncology 2024cited by 26position: middledoi
Osimertinib after definitive chemoradiotherapy in unresectable stage III epidermal growth factor receptor-mutated non-small-cell lung cancer: analyses of central nervous system efficacy and distant progression from the phase III LAURA study
Annals of Oncology 2024cited by 23position: middledoi
Longitudinal Analyses of Circulating Tumor DNA for the Detection of EGFR Mutation-Positive Advanced NSCLC Progression During Treatment: Data From FLAURA and AURA3
Journal of Thoracic Oncology 2024cited by 20position: middledoi
Osimertinib with or without Chemotherapy in <i>EGFR</i> -Mutated Advanced NSCLC
New England Journal of Medicine 2023cited by 627position: middledoi
Overall Survival with Osimertinib in Resected <i>EGFR</i> -Mutated NSCLC
New England Journal of Medicine 2023cited by 593position: middledoi
Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer
Nature Communications 2023cited by 231position: middledoi
Osimertinib in Resected <i>EGFR</i> -Mutated Non–Small-Cell Lung Cancer
New England Journal of Medicine 2020cited by 1,723position: middledoi
Osimertinib versus platinum–pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis
Annals of Oncology 2020cited by 275position: middledoi
Osimertinib as adjuvant therapy in patients (pts) with stage IB–IIIA EGFR mutation positive (EGFRm) NSCLC after complete tumor resection: ADAURA.
Journal of Clinical Oncology 2020cited by 96position: middledoi
Overall Survival with Osimertinib in Untreated, <i>EGFR</i> -Mutated Advanced NSCLC
New England Journal of Medicine 2019cited by 2,778position: middledoi
Tissue and Plasma EGFR Mutation Analysis in the FLAURA Trial: Osimertinib versus Comparator EGFR Tyrosine Kinase Inhibitor as First-Line Treatment in Patients with EGFR-Mutated Advanced Non–Small Cell Lung Cancer
Clinical Cancer Research 2019cited by 128position: middledoi
Postprogression Outcomes for Osimertinib versus Standard-of-Care EGFR-TKI in Patients with Previously Untreated EGFR-mutated Advanced Non–Small Cell Lung Cancer
Clinical Cancer Research 2019cited by 59position: middledoi
Overall survival (OS) from the AURA3 phase III study: Osimertinib vs platinum-pemetrexed (plt-pem) in patients (pts) with EGFR T790M advanced non-small cell lung cancer (NSCLC) and progression on a prior EGFR-tyrosine kinase inhibitor (TKI)
Annals of Oncology 2019cited by 30position: middledoi
Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study
Annals of Oncology 2018cited by 353position: middledoi
Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study
Annals of Oncology 2018cited by 40position: middledoi
Osimertinib in Untreated <i>EGFR</i> -Mutated Advanced Non–Small-Cell Lung Cancer
New England Journal of Medicine 2017cited by 5,202position: middledoi
Osimertinib vs standard of care (SoC) EGFR-TKI as first-line therapy in patients (pts) with EGFRm advanced NSCLC: FLAURA
Annals of Oncology 2017cited by 34position: middledoi
CNS response to osimertinib vs standard of care (SoC) EGFR-TKI as first-line therapy in patients (pts) with EGFR-TKI sensitising mutation (EGFRm)-positive advanced non-small cell lung cancer (NSCLC): Data from the FLAURA study
Annals of Oncology 2017cited by 33position: middledoi
Fulvestrant 500 mg vs 250 mg in postmenopausal women with estrogen receptor-positive advanced breast cancer: a randomized, double-blind registrational trial in China
Oncotarget 2016cited by 19position: middledoi
A randomized, phase III study (FLAURA) of AZD9291, a novel EGFR-TKI, versus gefitinib or erlotinib in treatment-naïve patients with advanced non-small cell lung cancer and an EGFR-TKI-sensitizing mutation.
Journal of Clinical Oncology 2015cited by 25position: middledoi
Abstract P1-13-07: A phase III study of fulvestrant 500 mg versus 250 mg in postmenopausal Chinese women with advanced breast cancer and disease progression following failure on prior antiestrogen or aromatase inhibitor therapy: Supporting superior clinical benefit for the
Cancer Research 2015cited by 1position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Suresh S. Ramalingam · Emory University11 papers (2015–2024)Margarita Majem · Hospital de Sant Pau9 papers (2018–2025)Jhanelle E. Gray · Moffitt Cancer Center9 papers (2017–2024)Jonathan W. Goldman · Industrial and Commercial Bank of China7 papers (2020–2025) · 7 papers (2017–2023)Ying Cheng · Changzhi University7 papers (2017–2025)Byoung Chul Cho · Université Grenoble Alpes7 papers (2017–2024)Thomas John · Austin Hospital7 papers (2019–2025)Yi‐Long Wu · China Agricultural University7 papers (2019–2025) · 6 papers (2018–2025)Thanyanan Reungwetwattana · Mahidol University6 papers (2017–2024)David Planchard · Institut Gustave Roussy5 papers (2017–2025)Wu‐Chou Su · National Cheng Kung University Hospital5 papers (2017–2023) · 5 papers (2017–2024)Rachel Hodge · Central Queensland University5 papers (2017–2020)К. К. Лактионов · Ministry of Health of the Russian Federation5 papers (2020–2025)Yuichiro Ohe · National Cancer Research Institute5 papers (2017–2023)Terufumi Kato · Kanagawa Prefectural Hospital Organization5 papers (2020–2025)Johan Vansteenkiste · University Hospital Heidelberg5 papers (2017–2019)Christian Grohé · Saarland University5 papers (2020–2025)
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