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Sandra J. Shefelbine

Northeastern University · US
Area of research
Surgery · Orthopedics and Sports Medicine
Research interest
Research interests include Bone health and osteoporosis research, Bone fractures and treatments, Hip disorders and treatments, and Osteoarthritis Treatment and Mechanisms.
h-index
46
citations
8,658
works
217
NIH funding
primary concept
email

Recent publications

Persistent postnatal IGF2 expression alters adult skeletal architecture in Igf2G/A mice
2026cited by 0position: contributordoi
Spatial and Temporal Variations of Viscoelastic Material Properties in Developing and Aging Goat Articular Cartilage
Journal of the Mechanical Behavior of Biomedical Materials 2026cited by 0position: contributordoi
Endochondral ossification: Insights into the cartilage mineralization processes achieved by an anhydrous freeze substitution protocol.
2025cited by 3position: contributordoi
Growth and patterning in vertebrate limb development A timescale perspective on skeletal specification
2025cited by 1position: contributordoi
A proximodistal gradient in bone structure and mechanics in the wings of Seba's short‐tailed bat, <i>Carollia perspicillata</i>
The Anatomical Record 2025cited by 0position: contributordoi
TRPV4 Inhibition Reduces Cartilage Growth During Axolotl Limb Regeneration
2025cited by 0position: contributordoi
Lost in research translation: Female athletes are not male athletes, especially at the hip
Journal of Orthopaedic Research® 2024cited by 8position: lastdoi
Lost in research translation: Female athletes are not male athletes, especially at the hip
Journal of Orthopaedic Research 2024cited by 8position: contributordoi
Material properties in regenerating axolotl limbs using inverse finite element analysis
Journal of the Mechanical Behavior of Biomedical Materials 2024cited by 4position: contributordoi
Analysis of bone structure in <i>PEROMYSCUS</i>: Effects of burrowing behavior
The Anatomical Record 2024cited by 2position: contributordoi
<scp>WISH</scp> ‐ <scp>BONE</scp> : Whole‐mount in situ histology, to label osteocyte <scp>mRNA</scp> and protein in <scp>3D</scp> adult mouse bones
The FASEB Journal 2024cited by 0position: contributordoi
Using Finite Element Modeling in Bone Mechanoadaptation
Current Osteoporosis Reports 2023cited by 41position: contributordoi
Can pelvic tilt cause cam morphology? A computational model of proximal femur development mechanobiology
Journal of Biomechanics 2023cited by 4position: contributordoi
Turing pattern prediction in three-dimensional domains: the role of initial conditions and growth
2023cited by 2position: contributordoi
Local mechanical stimuli correlate with tissue growth in axolotl salamander joint morphogenesis
Proceedings of the Royal Society B: Biological Sciences 2022cited by 9position: contributordoi
Adolescent obesity incurs adult skeletal deficits in murine induced obesity model
Journal of Orthopaedic Research 2022cited by 3position: contributordoi
Mechanoadaptation of the bones of mice with high fat diet induced obesity in response to cyclical loading
Journal of Biomechanics 2021cited by 7position: contributordoi
Measuring 3D growth plate shape: Methodology and application to cam morphology
Journal of Orthopaedic Research 2021cited by 2position: contributordoi
Local mechanical stimuli shape tissue growth in vertebrate joint morphogenesis
2021cited by 1position: contributordoi
A multi-scale modelling framework combining musculoskeletal rigid-body simulations with adaptive finite element analyses, to evaluate the impact of femoral geometry on hip joint contact forces and femoral bone growth
PLoS ONE 2020cited by 70position: middledoi
Murine Axial Compression Tibial Loading Model to Study Bone Mechanobiology: Implementing the Model and Reporting Results.
2020cited by 52position: contributordoi
3D visualization of macromolecule synthesis
eLife 2020cited by 16position: middledoi
3D visualization of macromolecule synthesis
eLife 2020cited by 14position: contributordoi
3D Visualization of Macromolecule Synthesis
2020cited by 0position: contributordoi
Author response: 3D visualization of macromolecule synthesis
2020cited by 0position: contributordoi
Murine Axial Compression Tibial Loading Model to Study Bone Mechanobiology: Implementing the Model and Reporting Results
Journal of Orthopaedic Research® 2019cited by 71position: middledoi
Validation of magneto-inertial measuring units for measuring hip joint angles
Journal of Biomechanics 2019cited by 27position: lastdoi
Age-associated changes in the response of tendon explants to stress deprivation is sex-dependent
Connective Tissue Research 2019cited by 23position: contributordoi
Increased Cellular Presence After Sciatic Neurectomy Improves the Bone Mechano-adaptive Response in Aged Mice
Calcified Tissue International 2019cited by 12position: contributordoi
Marrow aspiration in aged mice: intramedullary osteogenesis, reduced mechano-adaptation, increased marrow fat
Connective Tissue Research 2019cited by 0position: contributordoi

Grants

Collaborative Research: Bones and Burrowing: Mechanoadaptation in phylogeny, ontogeny and ecology of Peromyscus
NSF2529743$509,0002025–2028PIRePORTER
In Vivo Mechanotransduction During Limb Growth
NSF2318594$734,9722024–2026PIRePORTER
Manipulating Fluid Flow in Mechanoadaptation of Bone
NSF2010010$711,6602020–2025PIRePORTER
Mechanobiology of Joint Morphogenesis: Manipulating Salamander Limbs
NSF1727518$651,3002017–2021PIRePORTER
Heterogeneity and Anisotropy in Tough Materials
NSF1536354$444,9982015–2019PIRePORTER
Multi-scale Characteristics of Bone Toughness
NSF1436436$383,5582014–2018PIRePORTER
International Research Fellowship Program: Prediction of Bone Strength in Fracture Healing Using Quantitative Computed Tomography and Finite Element Analysis
NSF0202562$81,8402002–2004PIRePORTER

Frequent collaborators

· 25 papers (2019–2026) · 9 papers (2020–2025) · 8 papers (2020–2025) · 7 papers (2020–2025) · 4 papers (2020–2022)Judith Piet · Springer Nature4 papers (2019–2022)Jose J. Muñoz · Imperial College London4 papers (2021–2025)Vineel Kondiboyina · Northeastern University3 papers (2024–2026)Markus J. Buehler · Institute of Computing Technology3 papers (2014–2015)Baptiste Dépalle · Université Claude Bernard Lyon 12 papers (2014–2015)Quentin A Meslier · Washington University in St. Louis2 papers (2021–2024) · 2 papers (2021–2022)Julien Garnier · Northeastern University2 papers (2021–2022)Cara L Lewis · University of Massachusetts Boston2 papers (2021–2024)Soha Ben Tahar · Northeastern University2 papers (2023–2025)Cara L. Lewis · Boston University2 papers (2019–2024)Zhao Qin · Massachusetts Institute of Technology2 papers (2014–2015)J. Andrew Taylor · University of Nottingham1 papers (2017–2017)James R. Monaghan · Northeastern University1 papers (2020–2020)Georg Osterhoff · Unfallkrankenhaus Berlin1 papers (2016–2016)