Area of research
Physiology · Molecular Biology
Research interest
Research interests include Telomeres, Telomerase, and Senescence, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, and Genetics, Aging, and Longevity in Model Organisms.
Guidelines for minimal information on cellular senescence experimentation in vivo
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
Detection of senescence using machine learning algorithms based on nuclear features
Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome
Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement
Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy
Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH
LGG-09. SENOLYTIC AGENT NAVITOCLAX TARGETS VINBLASTINE- AND MAPK INHIBITORS-INDUCED SENESCENT TUMOUR CELLS IN PAEDIATRIC LOW GRADE GLIOMAS
Prostate carcinogenesis: inflammatory storms
Cellular Senescence: Defining a Path Forward
Cardiac glycosides are broad-spectrum senolytics
PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors
Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance
Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation