Area of research
Cancer Research · Genetics
Research interest
Research interests include Cancer-related molecular mechanisms research, MicroRNA in disease regulation, Glioma Diagnosis and Treatment, and Developmental Biology and Gene Regulation.
The evolution of gene regulation in mammalian cerebellum development
Oncogene aberrations drive medulloblastoma progression, not initiation
The evolution of gene regulation in mammalian cerebellum development
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Loss of Elp1 in cerebellar granule cell progenitors models ataxia phenotype of Familial Dysautonomia
Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma
Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
Cellular development and evolution of the mammalian cerebellum
Mapping pediatric brain tumors to their origins in the developing cerebellum
Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways
Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification
Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification
Renal Medullary Carcinomas Harbor a Distinct Methylation Phenotype and Display Aberrant Methylation of Genes Related to Early Nephrogenesis
Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells
Cellular development and evolution of the mammalian cerebellum
Mapping pediatric brain tumors to their origins in the developing cerebellum
The regulatory landscape of cells in the developing mouse cerebellum
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases
A theoretical model of neural maturation in the developing chick spinal cord
Acute manganese treatment restores defective autophagic cargo loading in Huntington’s disease cell lines
CDX4 regulates the progression of neural maturation in the spinal cord
Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line
Spatiotemporal analysis of zebrafish <i>hox</i> gene regulation by Cdx4