Area of research
Public Health, Environmental and Occupational Health · Immunology
Research interest
Research interests include Mosquito-borne diseases and control, Nitric Oxide and Endothelin Effects, Immune Cell Function and Interaction, and Neuroinflammation and Neurodegeneration Mechanisms.
Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease.
Combating respiratory diseases with mucosal vaccines.
First-in-human mRNA CAR therapy: Correlative biomarker analysis from the MT-302 phase 1 study targeting TROP2 in patients with advanced epithelial tumors.
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection.
Deep metabolic profiling of immune cells by spectral flow cytometry-A comprehensive validation approach.
Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis.
Faecal microbial transfer and complex carbohydrates mediate protection against COPD
Faecal microbial transfer and complex carbohydrates mediate protection against COPD.
A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants
A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants.
High-Dimensional Methods of Single-Cell Microglial Profiling to Enhance Understanding of Neuropathological Disease.
Interleukin-6 and interferon-alpha differentially regulate microglia function.
CD8<sup>+</sup> T Cells Mediate Lethal Lung Pathology in the Absence of PD-L1 and Type I Interferon Signalling following LCMV Infection.
NK cell profiling in West Nile virus encephalitis reveals potential metabolic basis for functional inhibition.
A unique human cord blood CD8<sup>+</sup>CD45RA<sup>+</sup>CD27<sup>+</sup>CD161<sup>+</sup> T-cell subset identified by flow cytometric data analysis using Seurat.
Therapeutic inhibition of glycolysis preferentially targets pathogenic monocyte subsets and attenuates CNS inflammation in flavivirus encephalitis
Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes.
Temporal tracking of microglial and monocyte single-cell transcriptomics in lethal flavivirus infection.
Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures.
Diet, commensal microbiota-derived extracellular vesicles, and host immunity.
FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design.
Clodronate is not protective in lethal viral encephalitis despite substantially reducing inflammatory monocyte infiltration in the CNS.
Putting PLX5622 into perspective: microglia in central nervous system viral infection.
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.
Role of MXRA8 in Ross River Virus Disease Pathogenesis.
TrackSOM: Mapping immune response dynamics through clustering of time-course cytometry data.
Novel role of GPR109A in thymic regulatory T cell development
Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function.
Integration, exploration, and analysis of high-dimensional single-cell cytometry data using Spectre.
Dietary protein increases T-cell-independent sIgA production through changes in gut microbiota-derived extracellular vesicles