Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Metabolomics and Mass Spectrometry Studies, Epigenetics and DNA Methylation, and Synthesis and biological activity.
Design and Synthesis of USP1 Inhibitors: Synergistic Antitumor Activity with PARP Inhibitors in Triple-Negative Breast Cancer.
Colorectal Cancer Cells Promote <i>de novo</i> Glycine Synthesis for Collagen Production in Cancer‐Associated Fibroblasts by Secreting TGF‐β1
Tumor biomarkers for diagnosis, prognosis and targeted therapy
Tumor biomarkers for diagnosis, prognosis and targeted therapy.
Epigenetic regulation in cancer therapy: From mechanisms to clinical advances
STK19 is a DNA/RNA-binding protein critical for DNA damage repair and cell proliferation.
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition.
Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
Discovery and Optimization of Novel <i>h</i>DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease.
Morphine Re-Arranges Chromatin Spatial Architecture of Primate Cortical Neurons
Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming
Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
A novel and potent dihydroorotate dehydrogenase inhibitor suppresses the proliferation of colorectal cancer by inducing mitochondrial dysfunction and DNA damage
DHODH and cancer: promising prospects to be explored.
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
Lipidomic profiling reveals lipid regulation by a novel LSD1 inhibitor treatment
The Novel LSD1 Inhibitor ZY0511 Suppresses Diffuse Large B Cell Lymphoma Proliferation by Inducing Apoptosis and Autophagy
Recent progress in treatment of hepatocellular carcinoma.
PubMed 2020cited by 302position: last
Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells
Targeting cellular metabolism to improve cancer therapeutics
Calcium phosphate embedded PLGA nanoparticles: A promising gene delivery vector with high gene loading and transfection efficiency