Area of research
Molecular Biology · Biomedical Engineering
Research interest
Research interests include RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques, Nanoparticle-Based Drug Delivery, and Nanoplatforms for cancer theranostics.
Hydrogels for RNA delivery
Nanodelivery of nucleic acids
Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy
Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Efferocytosis induces macrophage proliferation to help resolve tissue injury
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice
Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy
Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes <i>p53</i> -deficient cancers to mTOR inhibition
Biomimetic Nanosilica–Collagen Scaffolds for In Situ Bone Regeneration: Toward a Cell‐Free, One‐Step Surgery
RNA Nanotechnology-Mediated Cancer Immunotherapy
Orchestrated biomechanical, structural, and biochemical stimuli for engineering anisotropic meniscus
Multifunctional Fibers to Shape Future Biomedical Devices
Peptide-Based Autophagic Gene and Cisplatin Co-delivery Systems Enable Improved Chemotherapy Resistance
The siRNAsome: A Cation‐Free and Versatile Nanostructure for siRNA and Drug Co‐delivery
A Novel Top‐Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging‐Guided Cancer Therapy
Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA
Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance
Redox‐Responsive Nanoparticle‐Mediated Systemic RNAi for Effective Cancer Therapy
Antimonene Quantum Dots: Synthesis and Application as Near‐Infrared Photothermal Agents for Effective Cancer Therapy
ROS‐Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy
Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery <i>In Vitro</i> and <i>In Vivo</i>
Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in <i>Ldlr<sup>−/−</sup></i> Mice
Porphyrin/SiO<sub>2</sub>/Cp*Rh(bpy)Cl Hybrid Nanoparticles Mimicking Chloroplast with Enhanced Electronic Energy Transfer for Biocatalyzed Artificial Photosynthesis
Cancer nanomedicine: progress, challenges and opportunities
Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics
Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke
Ultra‐pH‐Responsive and Tumor‐Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti‐Cancer Efficacy
Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins
Nanotechnology for protein delivery: Overview and perspectives