Area of research
Infectious Diseases · Molecular Biology
Research interest
Research interests include Bedaquiline, Lipophilicity, hERG, Chemistry, Pharmacology, and Phospholipidosis.
Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis
3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel
Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline
Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology
Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles
6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis
Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units