Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Cellular Mechanics and Interactions, Stuttering Research and Treatment, RNA Research and Splicing, and Phonetics and Phonology Research.
Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility
Nuclear pore complexes concentrate on Actin/LINC/Lamin nuclear lines in response to mechanical stress in a SUN1 dependent manner
Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes
Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1
EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma
Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth
LIM proteins in actin cytoskeleton mechanoresponse
Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma
LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain
Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators
The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma