Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Mitochondrial Function and Pathology, Muscle metabolism and nutrition, Adipose Tissue and Metabolism, and Cancer, Hypoxia, and Metabolism.
Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
Insulin-regulated serine and lipid metabolism drive peripheral neuropathy
Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity
Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia
Daily running enhances molecular and physiological circadian rhythms in skeletal muscle
Serine restriction alters sphingolipid diversity to constrain tumour growth
Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function
Tolerance to graded dosages of histidine supplementation in healthy human adults
Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy