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Antoinette R. Tan

Levine Cancer Institute ·
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Advanced Breast Cancer Therapies, Cancer Treatment and Pharmacology, HER2/EGFR in Cancer Research, and Cancer Immunotherapy and Biomarkers.
h-index
43
citations
9,812
works
235
NIH funding
primary concept
Medicine
email

Recent publications

Breast Tumor-Bed Biopsy for Pathological Complete Response Prediction
JAMA Surgery 2025cited by 14position: middledoi
Trastuzumab Deruxtecan with Nivolumab in HER2-Expressing Metastatic Breast or Urothelial Cancer: Analysis of the Phase Ib DS8201-A-U105 Study
Clinical Cancer Research 2024cited by 36position: middledoi
Association Between Biomarkers and Clinical Outcomes of Pembrolizumab Monotherapy in Patients With Metastatic Triple-Negative Breast Cancer: KEYNOTE-086 Exploratory Analysis
JCO Precision Oncology 2023cited by 55position: middledoi
Abstract GS3-03: GS3-03 ARV-471, a PROTAC® estrogen receptor (ER) degrader in advanced ER-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer: phase 2 expansion (VERITAC) of a phase 1/2 study
Cancer Research 2023cited by 34position: middledoi
390P Vepdegestrant, a proteolysis targeting chimera (PROTAC) estrogen receptor (ER) degrader, in ER+/human epidermal growth factor receptor 2 (HER2)- advanced breast cancer: Update of dose escalation results from a phase I/II trial
Annals of Oncology 2023cited by 15position: middledoi
162O Primary analysis from DS8201-A-U105: A 2-part, open label, phase Ib trial assessing trastuzumab deruxtecan (T-DXd) with nivolumab (nivo) in patients (pts) with HER2-expressing advanced breast cancer
Annals of Oncology 2022cited by 36position: middledoi
Incidence and severity of anaphylaxis and hypersensitivity in trials of intravenous pertuzumab plus trastuzumab or the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection for HER2-positive breast cancer
European Journal of Cancer 2022cited by 6position: middledoi
First-in-Human, Phase 1 Dose-Escalation Study of Biparatopic Anti-HER2 Antibody–Drug Conjugate MEDI4276 in Patients with HER2-positive Advanced Breast or Gastric Cancer
Molecular Cancer Therapeutics 2021cited by 87position: middledoi
Abstract PD3-07: Trastuzumab deruxtecan (T-DXd; DS-8201) with nivolumab in patients with HER2-expressing, advanced breast cancer: A 2-part, phase 1b, multicenter, open-label study
Cancer Research 2021cited by 53position: middledoi
Targeted Treatment of Triple-Negative Breast Cancer
The Cancer Journal 2021cited by 16position: lastdoi
138P Anaphylaxis and hypersensitivity in trials of intravenous pertuzumab + trastuzumab (PH IV) or the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection (PH FDC SC) for HER2-positive breast cancer (BC)
Annals of Oncology 2021cited by 0position: middledoi
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors
Cancer Chemotherapy and Pharmacology 2020cited by 58position: middledoi
Abstract GS5-05: Primary analysis of NRG-BR005, a phase II trial assessing accuracy of tumor bed biopsies in predicting pathologic complete response (pCR) in patients with clinical/radiological complete response after neoadjuvant chemotherapy (NCT) to explore the feasibility of breast-conserving treatment without surgery
Cancer Research 2020cited by 43position: middledoi
Open-label Clinical Trial of Niraparib Combined With Pembrolizumab for Treatment of Advanced or Metastatic Triple-Negative Breast Cancer
JAMA Oncology 2019cited by 427position: middledoi
The current state of molecular testing in the treatment of patients with solid tumors, 2019
CA A Cancer Journal for Clinicians 2019cited by 260position: middledoi
Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study
Annals of Oncology 2018cited by 786position: middledoi
Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study
Annals of Oncology 2018cited by 624position: middledoi
Safety and Antitumor Activity of Pembrolizumab in Patients with Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer
Clinical Cancer Research 2018cited by 386position: lastdoi
TOPACIO/Keynote-162: Niraparib + pembrolizumab in patients (pts) with metastatic triple-negative breast cancer (TNBC), a phase 2 trial.
Journal of Clinical Oncology 2018cited by 77position: middledoi
Safety and pharmacokinetics of veliparib extended‐release in patients with advanced solid tumors: a phase I study
Cancer Medicine 2018cited by 20position: lastdoi
Relationship between tumor infiltrating lymphocyte (TIL) levels and response to pembrolizumab (pembro) in metastatic triple-negative breast cancer (mTNBC): Results from KEYNOTE-086
Annals of Oncology 2017cited by 185position: middledoi
Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)
Cancer Immunology Immunotherapy 2015cited by 150position: middledoi
Abstract S6-03: Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitors: A New York cancer consortium trial
Cancer Research 2015cited by 2position: middledoi
A phase 1 trial of E7974 administered on day 1 of a 21‐day cycle in patients with advanced solid tumors
Cancer 2012cited by 25position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Rita Nanda · Sun Pharma (India)6 papers (2017–2023)Sherene Loi · Peter MacCallum Cancer Centre5 papers (2017–2023)Sylvia Adams · South Texas Veterans Health Care System4 papers (2017–2023)Javier Cortés · Universidade Nova de Lisboa4 papers (2017–2023)Vassiliki Karantza · Merck & Co., Inc., Rahway, NJ, USA (United States)4 papers (2017–2023)Hope S. Rugo · UCSF Helen Diller Family Comprehensive Cancer Center4 papers (2017–2023)Erika Hamilton · Duke Medical Center4 papers (2021–2023)Michelino De Laurentiis · Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"3 papers (2017–2023)Deborah Toppmeyer · Rutgers, The State University of New Jersey3 papers (2017–2023)Charles L. Shapiro · Tisch Hospital3 papers (2015–2022)Melinda L. Telli · Stanford University3 papers (2018–2023)David W. Cescon · University Health Network3 papers (2017–2023)Sara A. Hurvitz · University of Washington Applied Physics Laboratory3 papers (2021–2023)Eric P. Winer · Yale University3 papers (2017–2023)Joyce O’Shaughnessy · Baylor University Medical Center3 papers (2018–2022)Bruce J. Dezube · Georgetown University3 papers (2015–2019)Peter Schmid · Cancer Research Institute3 papers (2017–2023)Hiroji Iwata · Juntendo University3 papers (2017–2023)Ahmad Awada · Institut Jules Bordet3 papers (2017–2023)Roberto Salgado · Université Libre de Bruxelles3 papers (2017–2023)