Area of research
Cognitive Neuroscience · Biomedical Engineering
Research interest
Link to Scott lab Research Interests My research focuses on how different regions of the brain are involved in motor control and learning. I have developed a robotic device called KINARM that can both sense and perturb planar arm movements. One of my research labs examines neural activity in different brain regions of non-human primates during motor behavior. A second lab explores human motor performance and learning. A third lab located at St. Mary’s of the Lake Hospital is used to quantify sensorimotor impairments in stroke and other neurological disorders. Sources of Research Funds: Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada, GlaxoSmithKline. Selected Publications Neural Basis of Movement: 1. Scott, S.H., Gribble, P. , Graham, K. and Cabel, D.W. (2001) Dissociation between hand motion and population vectors from neural activity in motor cortex. Nature 413:161-165. 2. Gribble, P.L. and Scott, S.H. (2002) Overlap of multiple internal models in primary motor cortex. Nature 417:938-941. 3. Kurtzer, I. Herter, T.M. and Scott, S.H. (2005) Random change in cortical load representation suggests distinct control of posture and movement. Nature Neuroscience 8:498-504. Human Motor Performance: 4. Nozaki, D., Kurtzer, I. and Scott, S.H. (2006) To learn with one limb or two? Limited transfer between unimanual and bimanual skills within the same limb. Nature Neuroscience 9:1364-1366. 5. Singh, K. and Scott, S.H. (2003) A motor learning strategy reflecting neural circuitry for limb control. Nature Neuroscience 6:399-403. Motor Function in Neurological Disorders: 6. Scott, S.H. and Norman, K.E. (2003) Computational approaches to motor control and their potential role for interpreting motor dysfunction. [Invited Review] Current Opinion in Neurology 16:693-698. Theories of Motor Control: 7. Scott, S.H. (2004) Optimal feedback control and the neural basis of motor control. Nature Reviews Neuroscience 5:532-546.
Identification of cognitive phenotypes in temporal lobe epilepsy and genetic generalized epilepsy using robotic assessment
Comparing the cognitive-motor performance of individuals with temporal lobe epilepsy versus healthy controls using robotics
Large Reaching Datasets Quantify the Impact of Age, Sex/Gender, and Experience on Motor Control
Non-Linear Modeling of Motor Development in Typically Developing Children and Youth Aged 5-18 Years Using Robot-Based Behavioral Assessments.
Rapid Online Corrections for Proprioceptive and Visual Perturbations Recruit Similar Circuits in Primary Motor Cortex.
Proprioceptive and Visual Feedback Responses in Macaques Exploit Goal Redundancy.
Capacity Limits Lead to Information Bottlenecks in Ongoing Rapid Motor Behaviors.
Integration of proprioceptive and visual feedback during online control of reaching.
Reverse Visually Guided Reaching in Patients with Parkinson's Disease.
Proprioceptive and visual feedback responses in macaques exploit goal redundancy
Assessment of spatiotemporal gait parameters using a deep learning algorithm-based markerless motion capture system
Transient deactivation of dorsal premotor cortex or parietal area 5 impairs feedback control of the limb in macaques
Rotational dynamics in motor cortex are consistent with a feedback controller.
Interjoint coupling of position sense reflects sensory contributions of biarticular muscles.
Author response: Rotational dynamics in motor cortex are consistent with a feedback controller
Maintained Representations of the Ipsilateral and Contralateral Limbs during Bimanual Control in Primary Motor Cortex.
Co-contraction uses dual control of agonist-antagonist muscles to improve motor performance
Maintained representations of the ipsilateral and contralateral limbs during bimanual control in primary motor cortex
Independent representations of ipsilateral and contralateral limbs in primary motor cortex.
Movement kinematics and proprioception in post-stroke spasticity: assessment using the Kinarm robotic exoskeleton
Visual Feedback Processing of the Limb Involves Two Distinct Phases.
Author response: Independent representations of ipsilateral and contralateral limbs in primary motor cortex
Localization of Impaired Kinesthetic Processing Post-stroke
Robotic Identification of Kinesthetic Deficits After Stroke
The independence of deficits in position sense and visually guided reaching following stroke
4. Nozaki, D., Kurtzer, I. and Scott, S.H. (2006) To learn with one limb or two? Limited transfer between unimanual and bimanual skills within the same limb. Nature Neuroscience 9:1364-1366.
— 2006cited by 0position: selected
3. Kurtzer, I. Herter, T.M. and Scott, S.H. (2005) Random change in cortical load representation suggests distinct control of posture and movement. Nature Neuroscience 8:498-504.
— 2005cited by 0position: selected
7. Scott, S.H. (2004) Optimal feedback control and the neural basis of motor control. Nature Reviews Neuroscience 5:532-546.
— 2004cited by 0position: selected
5. Singh, K. and Scott, S.H. (2003) A motor learning strategy reflecting neural circuitry for limb control. Nature Neuroscience 6:399-403.
— 2003cited by 0position: selected
6. Scott, S.H. and Norman, K.E. (2003) Computational approaches to motor control and their potential role for interpreting motor dysfunction. [Invited Review] Current Opinion in Neurology 16:693-698.
— 2003cited by 0position: selected