Area of research
Oncology · Immunology
Research interest
Research interests include CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, and Cancer Immunotherapy and Biomarkers.
A CD22-specific T-cell receptor enables effective adoptive T-cell therapy for B-cell malignancies
Selection of therapeutically effective T-cell receptors from the diverse tumor-bearing repertoire
Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry
One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication
CD4 <sup>+</sup> T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system
Oligonucleotide library screening for identification of virus‐specific T‐cell receptors
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
ERAP2 supports TCR recognition of three immunotherapy targeted tumor epitopes
Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3
Rapid single-cell identification of Epstein–Barr virus-specific T-cell receptors for cellular therapy
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma
Cooperation of genes in HPV16 <i>E6/E7</i>-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens
Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma
Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor–Engineered T Cells for Ovarian Cancer
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells
Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression
Chimeric PD-1:28 Receptor Upgrades Low-Avidity T cells and Restores Effector Function of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
Targeting human melanoma neoantigens by T cell receptor gene therapy
Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice
Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation
HEK293-Based Production Platform for γ-Retroviral (Self-Inactivating) Vectors: Application for Safe and Efficient Transfer of <i>COL7A1</i> cDNA
P72. Transgenic expression of a chimeric signaling receptor to facilitate T cell costimulation in the tumour environment
TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo
Human Antitumor CD8+ T Cells Producing Th1 Polycytokines Show Superior Antigen Sensitivity and Tumor Recognition