Area of research
Molecular Biology · Hematology
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, Hematopoietic Stem Cell Transplantation, and Ubiquitin and proteasome pathways.
Targeting MFGE8 secreted by cancer-associated fibroblasts blocks angiogenesis and metastasis in esophageal squamous cell carcinoma
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway
Identification of Gossypol Acetate as an Autophagy Modulator with Potent Anti-tumor Effect against Cancer Cells
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin
Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth
Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway
Genetic variants of 17q21 are associated with childhood‐onset asthma and related phenotypes in a northeastern Han Chinese population: a case–control study
Two mixed-NH3/amine platinum (II) anticancer complexes featuring a dichloroacetate moiety in the leaving group