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Hal S. Alper

University of Washington · US
Area of research
Molecular Biology · Biomedical Engineering
Research interest
Research interests include Microbial Metabolic Engineering and Bioproduction, Biofuel production and bioconversion, CRISPR and Genetic Engineering, and Viral Infectious Diseases and Gene Expression in Insects.
h-index
70
citations
18,002
works
252
NIH funding
primary concept
Chemistry
email

Recent publications

Space Biomanufacturing of Lactic Acid: Conceptual Design and Techno-Economic Analysis
ChemRxiv 2026cited by 0position: middledoi
Bioproduction, bioprotection, and biocontainment in multi-kingdom microbial systems with 3D spatial control.
2026cited by 0position: contributordoi
A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits.
2026cited by 0position: contributordoi
Theranostic Probiotic Engineered Living Materials That Dynamically Respond to Inflammation Markers.
2026cited by 0position: contributordoi
Real-time, <i>in situ</i> fluorescence and optical density measurements of liquid cultures in simulated microgravity
2026cited by 0position: contributordoi
Asking the 5 W's for designing next‐generation bioprocessing
AIChE Journal 2026cited by 0position: contributordoi
Engineering the yeast Yarrowia lipolytica for biomanufacturing
Current Opinion in Biotechnology 2026cited by 0position: contributordoi
Metabolic Engineering of &lt;i&gt;Yarrowia lipolytica&lt;/i&gt; for Conversion of Waste Cooking Oil into Omega-3 Eicosapentaenoic Acid.
2025cited by 7position: contributordoi
Recent advances in genetic engineering and chemical production in yeast species.
2025cited by 5position: contributordoi
Bioconversion yields must account for all carbon: hidden biases from complex media
Trends in Biotechnology 2025cited by 4position: contributordoi
Plastic degradation by enzymes from uncultured deep sea microorganisms.
2025cited by 2position: contributordoi
Developing a Yarrowia lipolytica platform for conversion of mannitol-containing waste streams
Bioresource Technology 2025cited by 1position: contributordoi
The Impact of Protein Content and Fouling on Enzymatic Degradation of Polyethylene Terephthalate.
2025cited by 0position: contributordoi
Single-cell phenotyping of extracellular electron transfer via microdroplet encapsulation.
2025cited by 0position: contributordoi
Bottlenecks in biobased approaches to plastic degradation.
2024cited by 40position: contributordoi
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.
2024cited by 32position: contributordoi
Leveraging a Y. lipolytica naringenin chassis for biosynthesis of apigenin and associated glucoside
Metabolic Engineering 2024cited by 13position: contributordoi
Advancing sustainable biotechnology through protein engineering
Trends in Biochemical Sciences 2024cited by 11position: contributordoi
A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules.
2024cited by 9position: contributordoi
Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in S. cerevisiae
Synthetic and Systems Biotechnology 2024cited by 8position: contributordoi
Engineered Living Material Bioreactors with Tunable Mechanical Properties using Vat Photopolymerization.
2024cited by 7position: contributordoi
Evolving dual-trait EPSP synthase variants using a synthetic yeast selection system.
2024cited by 5position: contributordoi
Considerations Regarding High Oil Density Bioreactor-Scale Fermentations of Yarrowia lipolytica Using CFD Modeling and Experimental Validation.
2024cited by 2position: contributordoi
Author Correction: A modular and synthetic biosynthesis platform for de novo production of diverse halogenated tryptophan-derived molecules.
2024cited by 1position: contributordoi
Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions
2024cited by 1position: contributordoi
Fluorescence-Based Screens for Engineering Enzymes Linked to Halogenated Tryptophan.
2024cited by 0position: contributordoi
A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits
2024cited by 0position: contributordoi
A tripartite microbial co-culture system for de novo biosynthesis of diverse plant phenylpropanoids.
2023cited by 37position: contributordoi
Gene expression dynamics in input-responsive engineered living materials programmed for bioproduction
Materials Today Bio 2023cited by 18position: contributordoi
Establishing a versatile toolkit of flux enhanced strains and cell extracts for pathway prototyping.
2023cited by 8position: contributordoi

Grants

Collaborative Research: CAS: A novel machine learning-assisted materials design cycle for bio-based thermosets
NSF2430717$380,8242025–2028PIRePORTER
Collaborative Research: Continuous Biomanufacturing using Decoupled Growth and Production Stages for Efficient Production and Recovery
NSF2133661$313,2592022–2025PIRePORTER
Collaborative Research: A New Yeast Biomanufacturing Platform for Making High-value Products from Oils and Fats
NSF1911469$301,5142020–2024PIRePORTER
Engineering Molecular Transport Proteins for Improved Xylose Uptake in Yeast
NSF1067506$360,7222012–2015PIRePORTER

Frequent collaborators

· 64 papers (2019–2026)Simon d’Oelsnitz · Center for Systems Biology10 papers (2021–2024)Andrew D. Ellington · Twitter (United States)9 papers (2021–2025) · 9 papers (2021–2025)Sierra M. Brooks · The University of Texas at Austin9 papers (2021–2026)Sarah Coleman · The University of Texas at Austin8 papers (2022–2026)Alshakim Nelson · Seton Hall University6 papers (2021–2026) · 5 papers (2021–2024) · 4 papers (2022–2025)Gokce Altin‐Yavuzarslan · University of Washington4 papers (2023–2026)Leqian Liu · Bruker (United States)3 papers (2017–2021)Adam R. Abate · City College of San Francisco3 papers (2017–2021)Gina Partipilo · The University of Texas at Austin3 papers (2024–2026)Shuo-Fu Yuan · National Taiwan University3 papers (2020–2023) · 3 papers (2022–2024)Michael C. Jewett · Indo-American Center3 papers (2021–2023)Benjamin K. Keitz · The University of Texas at Austin3 papers (2024–2026)Claire M. Palmer · The University of Texas at Austin2 papers (2018–2021)Shuo‐Fu Yuan · The University of Texas at Austin2 papers (2017–2018)James M. Wagner · Merck & Co., Inc., Rahway, NJ, USA (United States)2 papers (2017–2018)