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Han‐Shen Tae

University of Wollongong · AU
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Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Nicotinic agonist, Acetylcholine receptor, Chemistry, Conotoxin, Nicotinic acetylcholine receptor, and Pharmacology.
h-index
citations
767
works
49
NIH funding
primary concept
email

Recent publications

Cyclization of the Analgesic α‐Conotoxin Vc1.1 With a Non‐Natural Linker: Effects on Structure, Stability, and Bioactivity
Journal of Peptide Science 2025cited by 1position: middledoi
Erabutoxin mutants demonstrate interface selectivity at human fetal and adult muscle-type nicotinic acetylcholine receptors
Biochemical Pharmacology 2025cited by 1position: middledoi
Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channel
Biochemical Pharmacology 2024cited by 9position: firstdoi
N-Terminal Capping of the αO-Conotoxin Analogue GeX-2 Improves the Serum Stability and Selectivity toward the Human α9α10 Nicotinic Acetylcholine Receptor
Journal of Medicinal Chemistry 2024cited by 8position: middledoi
Development of an Intravenously Stable Disulfide-Rich Peptide for the Treatment of Chemotherapy-Induced Neuropathic Pain
Journal of Medicinal Chemistry 2024cited by 8position: middledoi
Dual Antagonism of α9α10 nAChR and GABA<sub>B</sub> Receptor-Coupled Ca<sub>V</sub>2.2 Channels by an Analgesic αO-Conotoxin Analogue
Journal of Medicinal Chemistry 2024cited by 7position: middledoi
Molecular determinants of the selectivity and potency of α-conotoxin Vc1.1 for human nicotinic acetylcholine receptors
Journal of Biological Chemistry 2024cited by 4position: firstdoi
Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors
Marine Drugs 2024cited by 2position: middledoi
Nicotinic acetylcholine receptors: Key targets for attenuating neurodegenerative diseases
The International Journal of Biochemistry & Cell Biology 2023cited by 24position: middledoi
Nicotinic acetylcholine receptor subtype expression, function, and pharmacology: Therapeutic potential of α-conotoxins
Pharmacological Research 2023cited by 21position: firstdoi
DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-<i>b</i>]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms
ACS Chemical Neuroscience 2023cited by 14position: firstdoi
Characterisation of Elevenin-Vc1 from the Venom of Conus victoriae: A Structural Analogue of α-Conotoxins
Marine Drugs 2023cited by 6position: middledoi
The Antinociceptive Activity of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)-N-methyl-N-(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor
Anesthesia & Analgesia 2023cited by 1position: middledoi
Mechanism of Action and Structure–Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor
Journal of Medicinal Chemistry 2022cited by 28position: middledoi
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider
Proceedings of the National Academy of Sciences 2022cited by 20position: middledoi
Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic Pseudogymnoascus sp. HDN17-933
Marine Drugs 2022cited by 6position: middledoi
Cysteine-Rich α-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor
ACS Chemical Neuroscience 2022cited by 4position: middledoi
Single-Disulfide Conopeptide Czon1107, an Allosteric Antagonist of the Human α3β4 Nicotinic Acetylcholine Receptor
Marine Drugs 2022cited by 4position: middledoi
Small-molecule mimicry hunting strategy in the imperial cone snail, <i>Conus imperialis</i>
Science Advances 2021cited by 27position: middledoi
Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models
Journal of Medicinal Chemistry 2021cited by 16position: middledoi
(E)-3-furan-2-yl-N-phenylacrylamide (PAM-4) decreases nociception and emotional manifestations of neuropathic pain in mice by α7 nicotinic acetylcholine receptor potentiation
Neurological Research 2021cited by 15position: middledoi
Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors
Biochemical Pharmacology 2021cited by 13position: firstdoi
α‐Conotoxin Bt1.8 from <i>Conus betulinus</i> selectively inhibits α6/α3β2β3 and α3β2 nicotinic acetylcholine receptor subtypes
Journal of Neurochemistry 2021cited by 8position: middledoi
Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor
Marine Life Science & Technology 2021cited by 6position: middledoi
Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor
Pharmacology & Therapeutics 2020cited by 45position: middledoi
Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels
Neuropharmacology 2020cited by 23position: middledoi
Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors
Journal of Medicinal Chemistry 2020cited by 22position: middledoi
(<i>E</i>)-3-Furan-2-yl-<i>N</i>-<i>p</i>-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation
ACS Chemical Neuroscience 2020cited by 20position: middledoi
Rational Design of α-Conotoxin RegIIA Analogues Selectively Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning
ACS Chemical Neuroscience 2020cited by 19position: middledoi
α-Conotoxin Vc1.1 Structure–Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement
ACS Chemical Neuroscience 2019cited by 22position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David J. Adams · University of Wollongong43 papers (2016–2025)Rilei Yu · Ministry of Education of the People's Republic of China18 papers (2016–2024)Tao Jiang · Anhui Medical University15 papers (2017–2024)David J. Craik · Australian Research Council8 papers (2016–2025)Hugo R. Arias · University of Oklahoma Health Sciences Center6 papers (2020–2024)Arsalan Yousuf · The University of Sydney5 papers (2020–2024)Richard J. Clark · University of Queensland4 papers (2016–2024) · 4 papers (2020–2024)Paul F. Alewood · The University of Queensland4 papers (2019–2022)Mahsa Sadeghi · Tehran University of Medical Sciences4 papers (2016–2021)Xiao Li · Sun Yat-sen University4 papers (2022–2024)Quentin Kaas · University of Queensland4 papers (2017–2019)Marcelo O. Ortells · Novartis (Switzerland)3 papers (2021–2024) · 3 papers (2020–2023)Lorenzo Di Cesare Mannelli · University of Florida3 papers (2020–2023)Zoltan Dekan · University of Queensland3 papers (2019–2022)R. Manjunatha Kini · National University of Singapore3 papers (2019–2025)James T. Daniel · University of Queensland3 papers (2016–2018)Tianmiao Li · South China Agricultural University3 papers (2024–2024)Bodil B. Carstens · University of Queensland3 papers (2016–2018)
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