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Stephan M. Tirier

German Cancer Research Center · DE
Area of research
Hematology · Cancer Research
Research interest
Research interests include Multiple Myeloma Research and Treatments, Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, and Cancer Cells and Metastasis.
h-index
10
citations
634
works
39
NIH funding
primary concept
email

Recent publications

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Nature Communications 2024cited by 14position: middledoi
Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Nature Communications 2024cited by 1position: middledoi
Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis
Blood 2023cited by 59position: middledoi
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level
Nature Communications 2023cited by 35position: middledoi
OA-23 Resolving therapy resistance mechanisms in multiple myeloma by multi-omics subclone analysis
Clinical Lymphoma Myeloma & Leukemia 2023cited by 2position: middledoi
ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats
Nucleic Acids Research 2022cited by 31position: middledoi
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 6position: middledoi
Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome
Blood 2022cited by 4position: middledoi
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics
Nature Communications 2021cited by 133position: firstdoi
Functional States in Tumor-Initiating Cell Differentiation in Human Colorectal Cancer
Cancers 2021cited by 21position: middledoi
The Spatial Heterogeneity in Newly Diagnosed Multiple Myeloma Patients - from Sub-Clonal Architecture to the Immune Microenvironment
Blood 2021cited by 6position: middledoi
OAB-007: Single-cell multiomic analysis identifies regulatory programs in relapsed/refractory multiple myeloma
Clinical Lymphoma Myeloma & Leukemia 2021cited by 1position: middledoi
P-049: The spatial sub-clonal architecture in newly diagnosed myeloma patients revealed by whole genome and single-cell sequencing
Clinical Lymphoma Myeloma & Leukemia 2021cited by 0position: middledoi
P-060: Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single cell transcriptomics
Clinical Lymphoma Myeloma & Leukemia 2021cited by 0position: middledoi
Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
Neuro-Oncology 2020cited by 169position: middledoi
Abstract 1491: Transcriptional heterogeneity identifies functional states of tumor-initiating cell differentiation in human colorectal cancer
Cancer Research 2020cited by 0position: middledoi
Pheno-seq – linking visual features and gene expression in 3D cell culture systems
Scientific Reports 2019cited by 26position: firstdoi
Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 8position: middledoi
A Comprehensive Analysis of Single-Cell Chromatin Accessibility and Gene Expression Identifies Intra-Tumor Heterogeneity and Molecular Treatment Responses in Relapsed/Refractory Multiple Myeloma
Blood 2019cited by 2position: middledoi
Dissecting Heterogeneity of Tumor Cells and Their Microenvironment in Refractory Multiple Myeloma
Blood 2019cited by 1position: firstdoi
Induced aneuploidy disrupts MCF10A acini formation and CCND1 expression
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 0position: middledoi
pheno-seq – linking 3D phenotypes of clonal tumor spheroids to gene expression
2018cited by 0position: first
pheno-seq – linking morphological features to gene expression in 3D cell culture systems
bioRxiv (Cold Spring Harbor Laboratory) 2018cited by 0position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Karsten Rippe · Hopp Children's Cancer Center Heidelberg14 papers (2018–2023)Jan‐Philipp Mallm · German Cancer Research Center12 papers (2018–2023)Simon Steiger · German Cancer Research Center10 papers (2018–2023)Katharina Bauer · German Cancer Research Center10 papers (2019–2023)Carsten Müller‐Tidow · Heidelberg University9 papers (2019–2023)Alexandra M. Poos · German Cancer Research Center9 papers (2019–2023)Niels Weinhold · Sylvester Comprehensive Cancer Center9 papers (2019–2023)Hartmut Goldschmidt · Virginia Cooperative Extension9 papers (2019–2023)Marc S. Raab · Memorial Sloan Kettering Cancer Center9 papers (2019–2023)Anja Baumann · University of Vienna9 papers (2019–2023)Lukas John · University of Hohenheim9 papers (2019–2023)Roland Eils · University of Michigan8 papers (2018–2021)Christian Conrad · Digital Health Cooperative Research Centre8 papers (2018–2021)Jeongbin Park · German Cancer Research Center7 papers (2018–2021)Nicola Giesen · Robert Bosch Hospital7 papers (2019–2023)Oliver Stegle · Institut thématique Génétique, génomique et bioinformatique7 papers (2019–2023)Stefanie Huhn · Heidelberg University5 papers (2021–2023)Hanno Glimm · Metropolitan University5 papers (2018–2021)Claudia R. Ball · German Cancer Research Center5 papers (2018–2021)Nina Prokoph · German Cancer Research Center5 papers (2021–2023)