Area of research
Nephrology · Molecular Biology
Research interest
Research interests include Inflammasome and immune disorders, Chronic Kidney Disease and Diabetes, Advanced Glycation End Products research, and Eicosanoids and Hypertension Pharmacology.
Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis
Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway
CD36 restricts lipid-associated macrophages accumulation in white adipose tissues during atherogenesis
Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice
Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease
Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress
Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy
PP2 Ameliorates Renal Fibrosis by Regulating the NF‐<i>κ</i>B/COX‐2 and PPAR<i>γ</i>/UCP2 Pathway in Diabetic Mice
ChREBP deficiency alleviates apoptosis by inhibiting TXNIP/oxidative stress in diabetic nephropathy
Effects of MiR-23b/ MAPK on renal fibrosis in rats with diabetic nephropathy
NQO1 Alleviates Renal Fibrosis by Inhibiting TLR4/NF-κB and TGF-β/Smad Signaling Pathway in Diabetic Nephropathy
Carbohydrate response element‐binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy
TXNIP deficiency mitigates podocyte apoptosis via restraining the activation of mTOR or p38 MAPK signaling in diabetic nephropathy
Thioredoxin‐interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy
NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction
Effects of sevoflurane preconditioning on postoperative cognitive dysfunction in aged rats
Effect of isoflurane on apoptosis of SH-SY5Y cells transfected with APPsw gene and the role of inositol 1,4,5-triphosphate receptors