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Michael T. Lotze

UPMC Hillman Cancer Center · US
Area of research
Immunology · Oncology
Research interest
Research interests include Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, and CAR-T cell therapy research.
h-index
135
citations
82,342
works
896
NIH funding
primary concept
email

Recent publications

Society for Immunotherapy of Cancer (SITC) consensus statement on essential biomarkers for immunotherapy clinical protocols
Journal for ImmunoTherapy of Cancer 2025cited by 34position: middledoi
The science of tumor-infiltrating lymphocytes (TIL): perspectives from the SITC Surgery Committee
Journal for ImmunoTherapy of Cancer 2025cited by 4position: lastdoi
A guideline on the molecular ecosystem regulating ferroptosis
Nature Cell Biology 2024cited by 238position: middledoi
The multifunctional protein HMGB1: 50 years of discovery
Nature reviews. Immunology 2023cited by 325position: lastdoi
AllergoOncology: Danger signals in allergology and oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper
Allergy 2022cited by 16position: middledoi
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
Journal for ImmunoTherapy of Cancer 2020cited by 1,043position: middledoi
CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer
Gut 2020cited by 118position: middledoi
Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19
Journal for ImmunoTherapy of Cancer 2020cited by 67position: middledoi
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee
Journal for ImmunoTherapy of Cancer 2020cited by 33position: middledoi
Clockophagy is a novel selective autophagy process favoring ferroptosis
Science Advances 2019cited by 476position: middledoi
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis
Annals of Oncology 2019cited by 246position: middledoi
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
Journal for ImmunoTherapy of Cancer 2019cited by 88position: middledoi
AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
Current Biology 2018cited by 734position: middledoi
The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
Cell Reports 2017cited by 932position: middledoi
HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Cancer Research 2017cited by 578position: middledoi
IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression
Neuro-Oncology 2016cited by 157position: middledoi
Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation
Alzheimer s & Dementia 2016cited by 32position: middledoi
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
Molecular & Cellular Oncology 2015cited by 478position: middledoi
Platelet-derived HMGB1 is a critical mediator of thrombosis
Journal of Clinical Investigation 2015cited by 364position: middledoi
Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation
Journal of Clinical Investigation 2015cited by 198position: middledoi
Consensus nomenclature for CD8<sup>+</sup>T cell phenotypes in cancer
OncoImmunology 2015cited by 136position: middledoi
HMGB1 in health and disease
Molecular Aspects of Medicine 2014cited by 962position: middledoi
Classification of current anticancer immunotherapies
Oncotarget 2014cited by 468position: middledoi
Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review
The Lancet Respiratory Medicine 2014cited by 214position: middledoi
The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics
Oncogene 2013cited by 232position: middledoi
Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice
Gastroenterology 2013cited by 206position: middledoi
The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma
Nature Reviews Clinical Oncology 2013cited by 198position: middledoi
Strange attractors: DAMPs and autophagy link tumor cell death and immunity
Cell Death and Disease 2013cited by 194position: middledoi
<scp>PAMP</scp>s and <scp>DAMP</scp>s: signal 0s that spur autophagy and immunity
Immunological Reviews 2012cited by 1,177position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Daolin Tang · Hubei University of Technology12 papers (2012–2023)Herbert J. Zeh · Southwestern Medical Center12 papers (2012–2023)Rui Kang · Yangzhou University11 papers (2012–2023)Timothy R. Billiar · Institute for Transfusion Medicine6 papers (2013–2017)Wen‐Chi Hou · UPMC Hillman Cancer Center4 papers (2013–2018)Guido Kroemer · Institut National du Cancer4 papers (2017–2020)Yangchun Xie · Central South University3 papers (2015–2018)Haichao Wang · Research Institute of Petroleum Exploration and Development3 papers (2013–2014)Shan Zhu · Massachusetts Eye and Ear Infirmary3 papers (2017–2019)Xiaorong Zhu · University of Chicago2 papers (2013–2015)Xinxin Song · Shanxi Agricultural University2 papers (2017–2018)Eugene B. Chang · University of Illinois Chicago2 papers (2013–2015)Lizhi Cao · Beijing Institute of Technology2 papers (2013–2014)Ruochan Chen · Central South University2 papers (2013–2014)Xuegong Fan · Central South University2 papers (2013–2014)Daniel J. Klionsky · University of Michigan2 papers (2018–2019)Minghua Yang · Central South University2 papers (2015–2019)Qiuhong Zhang · University of Pittsburgh2 papers (2013–2014)Xiaofang Sun · University of Science and Technology of China2 papers (2014–2017)Qingde Wang · University of Pittsburgh2 papers (2013–2014)