Area of research
Molecular Biology
Research interest
Research interests include Wnt/β-catenin signaling in development and cancer, Cancer-related gene regulation, Developmental Biology and Gene Regulation, and Congenital heart defects research.
Amino acid primed mTOR activity is essential for heart regeneration
Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis
Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness
Paratracheal air cyst in a foal
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping
ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells
Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish
WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner
First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor
Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds
Wnt/β-catenin signaling promotes regeneration after adult zebrafish spinal cord injury
Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling
Beyond canonical: The Wnt and β-catenin story
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros–derived hematopoietic stem cells
Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes
The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice
Wnt signaling induces transcription, spatial proximity, and translocation of fusion gene partners in human hematopoietic cells
Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors
Targeted BRAF Inhibition Impacts Survival in Melanoma Patients with High Levels of Wnt/β-Catenin Signaling
Botulinum Toxin Induces Muscle Paralysis and Inhibits Bone Regeneration in Zebrafish
Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt–β-catenin signaling
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)
WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma
Wnt/β-catenin signaling suppresses DUX4 expression and prevents apoptosis of FSHD muscle cells
Activation of Wnt/β-Catenin Signaling Increases Apoptosis in Melanoma Cells Treated with Trail
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