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J. J. Patten

Boston University · US
Area of research
Infectious Diseases · Computational Theory and Mathematics
Research interest
Research interests include Viral Infections and Outbreaks Research, SARS-CoV-2 and COVID-19 Research, Computational Drug Discovery Methods, and Viral Infections and Vectors.
h-index
14
citations
1,484
works
43
NIH funding
primary concept
email

Recent publications

Single-cell image-based screens identify host regulators of Ebola virus infection dynamics
Nature Microbiology 2025cited by 9position: middledoi
Design of universal Ebola virus vaccine candidates via immunofocusing
Proceedings of the National Academy of Sciences 2024cited by 19position: middledoi
A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential
Nature Communications 2024cited by 18position: middledoi
N-Substituted Pyrrole-Based Heterocycles as Broad-Spectrum Filoviral Entry Inhibitors
Journal of Medicinal Chemistry 2024cited by 6position: middledoi
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity
Nature Genetics 2023cited by 158position: middledoi
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein
iScience 2023cited by 8position: middledoi
Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization
iScience 2022cited by 29position: firstdoi
Anti‐SARS‐CoV‐2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID‐19 therapy
Journal of Medical Virology 2022cited by 22position: middledoi
Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19
Antiviral Research 2022cited by 17position: middledoi
Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer
Nature Cancer 2021cited by 159position: middledoi
Network medicine framework for identifying drug-repurposing opportunities for COVID-19
Proceedings of the National Academy of Sciences 2021cited by 117position: middledoi
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening
iScience 2021cited by 91position: middledoi
Inhibition of HECT E3 ligases as potential therapy for COVID-19
Cell Death and Disease 2021cited by 56position: middledoi
Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19
PubMed Central 2020cited by 520position: middledoi
Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
Molecular Cell 2020cited by 131position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Robert A. Davey · Boston University9 papers (2020–2025)Joseph Loscalzo · Broad Institute2 papers (2020–2021)Onur Varol · Northeastern University2 papers (2020–2021)Asher Ameli · Northeastern University2 papers (2020–2021)Xiao Gan · Pennsylvania State University2 papers (2020–2021)Deisy Morselli Gysi · Universidad del Noreste2 papers (2020–2021)Albert-Ĺaszló Barabási · Brigham and Women's Hospital2 papers (2020–2021)Mikołaj Słabicki · Broad Institute2 papers (2022–2023)Alex M. Jaeger · Moffitt Cancer Center2 papers (2021–2023)Ítalo Faria do Valle · Northeastern University2 papers (2020–2021)RuthMabel Boytz · Yale University2 papers (2022–2022)Haley Hauck · Massachusetts Institute of Technology2 papers (2021–2023)Mary C. Beytagh · Massachusetts Institute of Technology2 papers (2021–2023)Tyler Jacks · Howard Hughes Medical Institute2 papers (2021–2023)Nathan Sacks · Massachusetts Institute of Technology2 papers (2021–2023)Radosław P. Nowak · University of Bonn2 papers (2022–2023)Callum D. Owen · National Center of Infectious and Parasitic Diseases2 papers (2024–2024)Marinka Žitnik · Broad Institute2 papers (2020–2021)Zackery A. Ely · Broad Institute2 papers (2021–2023)Daniel Zhang · Gladstone Institutes2 papers (2021–2023)