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Vincent M. Christoffels

Newcastle University · GB
Area of research
Molecular Biology · Cardiology and Cardiovascular Medicine
Research interest
Research interests include Biology, Cell biology, Genetics, Mesenchyme, Gene, and Medicine.
h-index
citations
1,999
works
22
NIH funding
primary concept
email

Recent publications

The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis
Nature Communications 2025cited by 26position: middledoi
Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Nature Cardiovascular Research 2025cited by 15position: middledoi
TAD boundary deletion causes PITX2-related cardiac electrical and structural defects
Nature Communications 2024cited by 23position: middledoi
Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice
Cardiovascular Research 2023cited by 22position: middledoi
TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti
Nature Communications 2022cited by 51position: middledoi
Regulation of otocyst patterning by <i>Tbx2</i> and <i>Tbx3</i> is required for inner ear morphogenesis in the mouse
Development 2021cited by 45position: middledoi
Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries
Circulation Research 2021cited by 38position: middledoi
Lack of morphometric evidence for ventricular compaction in humans
Journal of Cardiology 2021cited by 38position: middledoi
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation
Circulation Research 2020cited by 82position: lastdoi
Conserved <i>NPPB</i> + Border Zone Switches From MEF2- to AP-1–Driven Gene Program
Circulation 2019cited by 107position: lastdoi
Identification of atrial fibrillation associated genes and functional non-coding variants
Nature Communications 2019cited by 92position: lastdoi
Loss-of-function variants in myocardin cause congenital megabladder in humans and mice
Journal of Clinical Investigation 2019cited by 47position: middledoi
TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme
Development 2018cited by 43position: middledoi
<i>Pitx2</i> modulates a <i>Tbx5</i> -dependent gene regulatory network to maintain atrial rhythm
Science Translational Medicine 2016cited by 154position: middledoi
Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung
Developmental Cell 2016cited by 76position: middledoi
A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference
EP Europace 2015cited by 142position: middledoi
A common genetic variant within SCN10A modulates cardiac SCN5A expression
Journal of Clinical Investigation 2014cited by 191position: middledoi
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
Nature Genetics 2013cited by 545position: middledoi
Tbx2 Controls Lung Growth by Direct Repression of the Cell Cycle Inhibitor Genes Cdkn1a and Cdkn1b
PLoS Genetics 2013cited by 82position: middledoi
Inhibition of Sox2-dependent activation of <i>Shh</i> in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis
Development 2013cited by 69position: middledoi
Tbx2 Terminates Shh/Fgf Signaling in the Developing Mouse Limb Bud by Direct Repression of Gremlin1
PLoS Genetics 2013cited by 57position: middledoi
Homeobox transcription factor Pitx2: The rise of an asymmetry gene in cardiogenesis and arrhythmogenesis
Trends in Cardiovascular Medicine 2013cited by 54position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Andreas Kispert · Medizinische Hochschule Hannover7 papers (2013–2022)Timo H. Lüdtke · Medizinische Hochschule Hannover6 papers (2013–2022)Carsten Rudat · Medizinische Hochschule Hannover5 papers (2013–2022)Mark‐Oliver Trowe · Medizinische Hochschule Hannover4 papers (2013–2022) · 4 papers (2013–2019)James F. Martin · Baylor College of Medicine4 papers (2016–2020)Ivan P. Moskowitz · University of Chicago3 papers (2014–2020)Henner F. Farin · Goethe University Frankfurt3 papers (2013–2016)Anne Moon · Geisinger Medical Center3 papers (2016–2021)Marina Kaiser · Medizinische Hochschule Hannover3 papers (2018–2022) · 2 papers (2019–2020)Marianne Petry · Medizinische Hochschule Hannover2 papers (2013–2013)Marcelo A. Nóbrega · University of Chicago2 papers (2014–2019)Irina Wojahn · Medizinische Hochschule Hannover2 papers (2016–2021)Ingeborg van der Made · Ludwig-Maximilians-Universität München2 papers (2019–2019)Bastiaan J. Boukens · University of Massachusetts Amherst2 papers (2016–2019)Esther E. Creemers · Utrecht University2 papers (2019–2019)Rangarajan D. Nadadur · Gladstone Institutes2 papers (2016–2020)Patrick T. Ellinor · Icahn School of Medicine at Mount Sinai2 papers (2019–2020) · 2 papers (2019–2025)