Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Amyotrophic Lateral Sclerosis Research, and Parkinson's Disease Mechanisms and Treatments.
Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing
G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease
Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia
Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states
Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis
Cross-disorder and disease-specific pathways in dementia revealed by single-cell genomics
Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
Comprehensive mapping of synaptic vesicle protein 2A (SV2A) in health and neurodegenerative diseases: a comparative analysis with synaptophysin and ground truth for PET-imaging interpretation
Biomarker‐Based Approach to α‐Synucleinopathies: Lessons from Neuropathology
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes
Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils
Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations
Alzheimer's disease phenotypes show different sleep architecture
Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations
FTLD targets brain regions expressing recently evolved genes
Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases
Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinicopathological Case Series
Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease
Comorbid neuropathological diagnoses in early versus late-onset Alzheimer’s disease
Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology