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M. James You

The University of Texas MD Anderson Cancer Center · US
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Area of research
Hematology · Pathology and Forensic Medicine
Research interest
Research interests include Acute Myeloid Leukemia Research, Lymphoma Diagnosis and Treatment, Acute Lymphoblastic Leukemia research, and Chronic Myeloid Leukemia Treatments.
h-index
48
citations
12,116
works
242
NIH funding
primary concept
Biology
email

Recent publications

Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML
Cancer Biology & Therapy 2025cited by 1position: middledoi
A global study for acute myeloid leukemia with <i>RARG</i> rearrangement
Blood Advances 2023cited by 26position: middledoi
LMO2 expression is frequent in T-lymphoblastic leukemia and correlates with survival, regardless of T-cell stage
Modern Pathology 2022cited by 21position: middledoi
Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance
Cancer Discovery 2022cited by 19position: middledoi
A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
Nature Communications 2021cited by 336position: middledoi
Downregulation of <i>FAPP2</i> gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T‐cell acute lymphoblastic leukemia
Hematological Oncology 2021cited by 8position: middledoi
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
Nature Cell Biology 2020cited by 586position: middledoi
Acute myeloid leukemia with a novel CPSF6‐RARG variant is sensitive to homoharringtonine and cytarabine chemotherapy
American Journal of Hematology 2019cited by 25position: lastdoi
Long noncoding RNA MALAT1 suppresses breast cancer metastasis
Nature Genetics 2018cited by 817position: middledoi
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration
Nature 2018cited by 295position: middledoi
Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis
Journal of Clinical Investigation 2017cited by 94position: middledoi
Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD
Leukemia 2017cited by 63position: lastdoi
HDAC6 regulates microRNA-27b that suppresses proliferation, promotes apoptosis and target MET in diffuse large B-cell lymphoma
Leukemia 2017cited by 62position: middledoi
Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers
Clinical Cancer Research 2016cited by 184position: middledoi
Prognostic Factors of Hepatosplenic T-cell Lymphoma
The American Journal of Surgical Pathology 2016cited by 82position: middledoi
p53 Activity Dominates That of p73 upon <i>Mdm4</i> Loss in Development and Tumorigenesis
Molecular Cancer Research 2015cited by 6position: middledoi
Breast implant-associated anaplastic large cell lymphoma: sensitivity, specificity, and findings of imaging studies in 44 patients
Breast Cancer Research and Treatment 2014cited by 159position: middledoi
Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment
Blood 2014cited by 61position: middledoi
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia
Blood 2013cited by 220position: middledoi
Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP
Modern Pathology 2013cited by 128position: middledoi
EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis
Molecular Cell 2012cited by 242position: middledoi
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia
Oncogene 2012cited by 92position: middledoi
Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts
Leukemia 2012cited by 23position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

L. Jeffrey Medeiros · Universidade Federal de Pernambuco4 papers (2013–2017)Li Ma · Jiangsu University3 papers (2017–2021)Roberto N. Miranda · The University of Texas MD Anderson Cancer Center3 papers (2014–2017)Ya‐Ling Yang · Nanchang University3 papers (2017–2025)Boyi Gan · The University of Texas MD Anderson Cancer Center3 papers (2018–2021)Francisco Vega · The University of Texas MD Anderson Cancer Center3 papers (2014–2022)Ken H. Young · Duke Medical Center3 papers (2013–2016)Xianbao Huang · Nanchang University2 papers (2019–2025)Guilin Tang · Jilin University2 papers (2016–2019) · 2 papers (2013–2017)Andrew P. Weng · Terry Fox Research Institute2 papers (2012–2017)Yutong Sun · Hebei Medical University2 papers (2018–2021)Michelle A. Fanale · Pfizer (United States)2 papers (2014–2016)Wei Li · Harbin Medical University2 papers (2017–2020)Xiaoguang Liu · Beijing Technology and Business University2 papers (2020–2021)Yilei Zhang · University of Canterbury2 papers (2020–2021)Hyemin Lee · The University of Texas MD Anderson Cancer Center2 papers (2018–2020)George A. Călin · The University of Texas MD Anderson Cancer Center2 papers (2013–2017)Govind Bhagat · Columbia University Irving Medical Center2 papers (2013–2016)Fan Yao · Changsha Medical University2 papers (2018–2021)
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